P-1248 - First Episode of Psychosis: Stability of the Clinical Diagnostic After 10 Years of Evolution

Abstract

Introduction

One of the main validation criteria for psychotic disorders is the stability over time.

Objectives

The diagnostic evaluation of a group of subjects who presented with a first episode of psychosis, after 10 years of evolution.

Aim

To evidence certain factors that might be associated with diagnostic stability.

Method

The study was conducted on a sample of 79 patients who had a first admission in the Psychiatry Clinic of Timisoara, between 1999–2000. There was a cross-sectional analysis of the sample at three intervals (at onset and after 5, respectively 10 years). The parameters we have observed were, as follows: socio-demographical (gender, age at onset, educational level) and clinical-evolutionary (diagnostic, according to the ICD-10).

Results

At the last evaluation, the sample consisted of only 48 subjects, of which 22 (45.83%) had no change in diagnostic, other 22 subjects (45.83%) had suffered a change in diagnostic during the first 5 years after onset, and 4 more subjects (8.33%) had had a change in diagnostic during the first 10 years of evolution. The onset diagnostics, F23 and F32, had later changed towards a different nosological framing. We could not evidence any factors that had an influence on the stability of the diagnostic over time.

Conclusions

The stability of the clinical diagnostic is not a main coordinate of the first episode of psychosis.