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EPA-1607 - Underlying Mechanisms of Placebo Effect. an Integrative View

Published online by Cambridge University Press:  15 April 2020

E. Gimeno
Affiliation:
Department of Basic Psychology Psychobiology and Methodology of Behavioral Sciences., University of Salamanca Salamanca Spain., Salamanca, Spain
P. Ruisoto
Affiliation:
Department of Basic Psychology Psychobiology and Methodology of Behavioral Sciences., University of Salamanca Salamanca Spain., Salamanca, Spain

Abstract

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Introduction

Placebo effect has been a controversial and hot topic within psychoneuroinmunology. However recent studies have shed considerable light on the potential mechanisms of placebo responses and their role in health outcomes.

Aim and objectives

This study aims to provide a new and integrative look at the neurobiological mechanisms underlying the placebo effect.

Methods

A systematic review was conducted for articles published in peer-review journals in the last decade.

Results

The two most evidence-based neural pathways for placebo effect: dopamine-related and endorphine-related; are fully explained and integrated in a comprehensive view.

Conclusions

The placebo effect represents an example of well-documented mind effect on the body. Implications for stress-related diseases are discussed.

Type
P25 - Psychoneuroimmunology
Copyright
Copyright © European Psychiatric Association 2014
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