Hostname: page-component-78c5997874-g7gxr Total loading time: 0 Render date: 2024-11-02T19:05:49.317Z Has data issue: false hasContentIssue false

Empirical validation of the wcst network structure in patients

Published online by Cambridge University Press:  13 August 2021

G. Gil-Berrozpe*
Affiliation:
Mental Health Group, Instituto de Investigación Sanitaria de Navarra (IdISNA), Pamplona, Spain
A. Sánchez-Torres
Affiliation:
Mental Health Group, Instituto de Investigación Sanitaria de Navarra (IdISNA), Pamplona, Spain
L. Moreno-Izco
Affiliation:
Mental Health Group, Instituto de Investigación Sanitaria de Navarra (IdISNA), Pamplona, Spain
R. Lorente-Omeñaca
Affiliation:
Mental Health Group, Instituto de Investigación Sanitaria de Navarra (IdISNA), Pamplona, Spain
A. Ballesteros
Affiliation:
Mental Health Group, Instituto de Investigación Sanitaria de Navarra (IdISNA), Pamplona, Spain
Á.S. Rosero
Affiliation:
Mental Health Group, Instituto de Investigación Sanitaria de Navarra (IdISNA), Pamplona, Spain
V. Peralta
Affiliation:
Mental Health Group, Instituto de Investigación Sanitaria de Navarra (IdISNA), Pamplona, Spain
M. Cuesta
Affiliation:
Mental Health Group, Instituto de Investigación Sanitaria de Navarra (IdISNA), Pamplona, Spain
*
*Corresponding author.

Abstract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.
Introduction

Cognitive impairment is a core feature of schizophrenia and other psychotic disorders and executive deficits are within the most impaired cognitive functions The Wisconsin Card Sorting test (WCST) has been extensively used in literature on schizophrenia and psychosis. The underlying structure of executive impairment may have important implications for our understanding of the complex connections between executive dysfunction and the psychopathology and neurofunctional basis of psychosis.

Objectives

The objective was to empirically validate the dimensions of the WCST network structure of patients regarding antecedent, concurrent and outcome variables.

Methods

Subjects were 298 patients with a DSM 5 diagnosis of psychotic disorder. To assess the empirical validation of network structure of the WCST antecedent, concurrent and outcome variables were selected from the CASH interview and other scales of patients.

Results

Pearson coefficient correlations between the 4 network loadings (NL) of WCST, namely perseveration, inefficient sorting, failure to maintain the set and learning, and antecedent, concurrent and outcome validators are shown in the table. PER and IS showed common and strong associations with antecedent, concurrent and outcome validators. LNG dimension was also moderately associated and FMS did not show significant associations.

Conclusions

‘Perseveration’ and ‘Inefficient sorting’ dimensions achieve and share common antecedent, concurrent and outcome validators. While ‘Learning’ dimension achieves partial validation in terms of antecedent and outcome validators and ‘Failure to maintain the set’ dimension was not associated with external validators. These four underlying dysfunctions might help to disentangle the neurofunctional basis of executive deficits in psychosis.

Type
Abstract
Creative Commons
Creative Common License - CCCreative Common License - BY
This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
Copyright
© The Author(s), 2021. Published by Cambridge University Press on behalf of the European Psychiatric Association
Submit a response

Comments

No Comments have been published for this article.