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Current Controversies in Antidepressant Therapy: A Patient-level Perspective

Published online by Cambridge University Press:  19 July 2023

F. Hieronymus
F. Hieronymus*
Affiliation:
1Department of Clinicla Medicine, Aarhus University, Aarhus, Denmark 2Institute of Neuroscience and Physiology, University of Gothenburg, Gothenburg, Sweden

Abstract

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Abstract

The value of pharmacological antidepressants have been contested since they were first introduced in the 1960s, but the points of contention have varied over time. This session will examine and critically discuss some of the concerns that are commonly voiced today, with particular emphasis on the evaluation of efficacy. The session will cover topics such as the utility of dichotomized outcome measures (e.g., response and remission) and whether the use of these measures risk inflating apparent efficacy, whether antidepressant effect sizes are too small to be clinically meaningful, and whether there is individual variability in the response to pharmacological antidepressants.

Disclosure of Interest

F. Hieronymus Speakers bureau of: I have received speaker’s fees from Janssen and H Lundbeck.

Type
Abstract
Information
European Psychiatry , Volume 66 , Special Issue S1: Abstracts of the 31st European Congress of Psychiatry , March 2023 , pp. S9
Creative Commons
Creative Common License - CCCreative Common License - BY
This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
Copyright
© The Author(s), 2023. Published by Cambridge University Press on behalf of the European Psychiatric Association
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