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Cholesterol concentrations in violent and non-violent women suicide attempters

Published online by Cambridge University Press:  16 April 2020

J. Vevera*
Affiliation:
Psychiatric Clinic, 1st Medical Faculty, Charles University of Prague, Prague, Czech Republic School of Public Health, University of California at Berkeley, 140 Warren Hall, MC7360, Berkeley, CA 94720, USA
I. Žukov
Affiliation:
Psychiatric Clinic, 1st Medical Faculty, Charles University of Prague, Prague, Czech Republic
T. Morcinek
Affiliation:
Psychiatric Hospital in Bohnice, Prague, Czech Republic
H. Papežová
Affiliation:
Psychiatric Clinic, 1st Medical Faculty, Charles University of Prague, Prague, Czech Republic
*
*E-mail address: [email protected]
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Abstract

The aim of this study was to evaluate whether women with a history of violent suicide attempts have lower serum cholesterol concentrations than those who attempted suicide by non-violent methods. Our retrospective study used a case-control design to compare serum total cholesterol concentration, hematocrit, red blood cell count and body mass index (BMI) in women with a history of violent (n = 19) or non-violent (n = 51) suicide attempts and of non-suicidal controls (n = 70) matched by diagnosis and age. Analysis of covariance (ANCOVA) with age as the covariate was used to analyze differences in cholesterol levels in groups according to violence. Violence was found to be a significant factor (P = 0.016). Using the Scheffé test, a significant difference (P = 0.011) was revealed between the group of violent and non-violent suicide attempters and between the violent suicide attempters and the control group. Patients with a violent suicidal attempt have significantly lower cholesterol levels than patients with non-violent attempts and the control subjects. Our findings suggest that suicide attempts should not be considered a homogenous group. They are consistent with the theory that low levels of cholesterol are associated with increased tendency for impulsive behavior and aggression and contribute to a more violent pattern of suicidal behavior.

Type
Original article
Copyright
Copyright © Éditions scientifiques et médicales Elsevier SAS 2003

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