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The virulence of strains of poliovirus for cynomolgus monkeys after subcutaneous injection

Published online by Cambridge University Press:  15 May 2009

C. R. Coid ,
T. S. L. Beswick  and
J. O'H. Tobin
C. R. Coid
Affiliation:
Biological Standards Control Laboratory, Medical Research Council Laboratories, Hampstead, London, N.W. 3
T. S. L. Beswick
Affiliation:
Biological Standards Control Laboratory, Medical Research Council Laboratories, Hampstead, London, N.W. 3
J. O'H. Tobin
Affiliation:
Biological Standards Control Laboratory, Medical Research Council Laboratories, Hampstead, London, N.W. 3
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The virulence of strains of the three types of poliovirus have been examined by the subcutaneous injection of monkeys. The strains used were the Sabin attenuated Types 1, 2 and 3, Cox attenuated Types 1, 2 and 3, the Brunenders Type 1 partially attenuated strain, MEF-1, Type 2 and Saukett, Type 3.

The results obtained indicated that the subcutaneous route of injection offers a promising method for comparing and characterizing strains of poliovirus.

Type
Research Article
Information
Journal of Hygiene , Volume 59 , Issue 4 , December 1961 , pp. 387 - 394
Copyright
Copyright © Cambridge University Press 1961

References

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