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Geographical and temporal distribution of Ockelbo disease in Sweden

Published online by Cambridge University Press:  19 October 2009

J. O. Lundström ,
S. Vene ,
Å. Espmark ,
M. Engvall  and
B. Niklasson
J. O. Lundström
Affiliation:
Department of Virology, National Bacteriological Laboratory, S-10521 Stockholm, Sweden Department of Virology, Karolinska Institute, c/o National Bacteriological Laboratory, S-10521 Stockholm, Sweden
S. Vene
Affiliation:
Department of Virology, National Bacteriological Laboratory, S-10521 Stockholm, Sweden
Å. Espmark
Affiliation:
Department of Virology, National Bacteriological Laboratory, S-10521 Stockholm, Sweden
M. Engvall
Affiliation:
Department of Virology, National Bacteriological Laboratory, S-10521 Stockholm, Sweden
B. Niklasson
Affiliation:
Department of Virology, National Bacteriological Laboratory, S-10521 Stockholm, Sweden National Defence Research Establishment, FOA-5, S-17290 Sundyberg,Sweden
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Summary

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The incidence of Ockelbo disease and the prevalence of Ockelbo virus neutralizing antibodies were investigated in a sample of the Swedish population. The disease occurs throughout most of Sweden but with higher incidence and antibody prevalence rates in the central part of the country. It generally affects middle-aged men and women, with equal incidence between sexes, and is uncommon in people younger than 20 years of age. The disease occurs during a short period each year between the third week of July and the first week of October, with a peak during the second half of August. During the 8 years studied (1981–8), an average of 31 Ockelbo patients/year were diagnosed. The antibody prevalence rates in the oldest age groups were 20–40 times higher than the accumulated life-risk of being diagnosed and reported as an Ockelbo disease patient, which suggests that many cases are asymptomatic and/or unreported.

Type
Research Article
Information
Epidemiology & Infection , Volume 106 , Issue 3 , June 1991 , pp. 567 - 574
Copyright
Copyright © Cambridge University Press 1991

References

REFERENCES

1.Espmark, Å, Niklasson, B.Ockelbo disease in Sweden: Epidemiological, clinical and virological data from the 1982 outbreak. Am J Trop Med Hyg 1984; 33: 1203–11.CrossRefGoogle ScholarPubMed
2.Niklasson, B, Espmark, A, Lundström, Jo.Occurrence of arthralgia and specific IgM antibodies three to four years after Ockelbo disease. J Inf Dis 1988; 157: 832–5.CrossRefGoogle ScholarPubMed
3.Skogh, M, Espmark, A.Ockelbo disease: epidemic arthritis-exanthema syndrome in Sweden caused by a Sindbis–virus like agent. Lancet 1982; i: 795–6.CrossRefGoogle Scholar
4.Niklasson, B, Espmark, A, LeDuc, Jw et al. Association of a Sindbis-like virus with Ockelbo disease in Sweden. Am J Trop Med Hyg 1984; 33: 1212–7.CrossRefGoogle ScholarPubMed
5.Calisher, Ch, Karabatsos, N, Lazuick, Js, Monath, T, Wolff, C.Reevaluation of the western equine encephalitis antigenic complex of alphaviruses (family Togaviridae) as determined by neutralization tests. Am J Trop Med Hyg 1988; 38: 447–52.CrossRefGoogle ScholarPubMed
6.Lvov, Dk, Vladimirtseva, Ea, Butenko, Am, Karabatsos, N, Trent, Dw, Calisher, ChIdentity of Karelian fever and Ockelbo viruses determined by serum dilution-plaque reduction neutralization tests and oligonucleotide mapping. Am J Trop Med Hyg 1988; 39: 607–10.CrossRefGoogle ScholarPubMed
7.Lvov, Dk, Skvortsova, Tm, Kondrashina, Ng et al. Etiology of Karelian fever – a new arbovirus infection. Vopr Virusol 1982; 27: 690–2.Google Scholar
8.Brummer-Korvenkontio, M, Kuusisto, P. Pogosta disease. In: TM, Skvortsova, Sidorova, Ga, Berezina, Lk, Fomina, B, Yakolev, Vi, Bobrovskikh, Tk, eds. Proceedings of the Sovietr-Finnish symposium on etiology, epidemiology, diagnosis and prophylaxis of Karelian fever – Potosta disease. Perozavodsk: Academy of Medical Sciences, USSR, 1984: 23.Google Scholar
9.McLntosh, Bm, McGillivray, Gm, Dickinson, DbIllness caused by Sindbis and West Nile viruses in South Africa. S Afr Med J 1964; 38: 291–4.Google Scholar
10.Doherty, Rl, Bodey, As, Carew, JsSindbis virus infection in Australia. Med J Aust 1969; 2: 1016–7.CrossRefGoogle ScholarPubMed
11.McLntosh, Bm, Jupp, Pg, Dos Santos, J, Meenehan, GmEpidemics of West Nile and Sindbis viruses in South Africa with Culex (Culex) univittatus Theobald as vector. S Afr J Sci 1976; 72: 295–300.Google Scholar
12.Jupp, Pg, Blackburn, Nk, Thompson, L, Meenehan, Gm.Sindbis and West Nile virus infections in the Witwatersrand-Pretoria region. S Afr Med J 1986; 70: 218–20.Google ScholarPubMed
14.Francy, Db, Jaenson, Tgt, Lundström, Jo et al. Ecologic studies of mosquitoes and birds as hosts of Ockelbo virus in Sweden and isolation of Inkoo and Batai viruses from mosquitoes. Am J Trop Med Hyg 1989; 41: 355–63.CrossRefGoogle ScholarPubMed
15.Lundström, Jo, Francy, Db, Niklasson, B.Swedish Culex torrentium and Cx. pipiens (Diptera: Culicidae) as experimental vector of Ockelbo virus. J Med Entomol 1990; 27: 561–3.CrossRefGoogle ScholarPubMed
16.Turell, Mj, Lundström, Jo, Niklasson, B.Transmission of Ockelbo virus with Aedes cinereus, Aedea communis, and Aedes excrucians (Diptera: Culicidae) collected in an enzootic area in central Sweden. J Med Entomol 1990; 27: 266–8.CrossRefGoogle Scholar