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Use of routine ventricular assist following the first stage Norwood procedure

Published online by Cambridge University Press:  21 September 2005

Ross M. Ungerleider
Affiliation:
Department of Cardiac Surgery, Doernbecher Children's Hospital, Oregon Health and Sciences University, Portland, Oregon, USA
Irving Shen
Affiliation:
Department of Cardiac Surgery, Doernbecher Children's Hospital, Oregon Health and Sciences University, Portland, Oregon, USA
Grant Burch
Affiliation:
Department of Cardiac Surgery, Doernbecher Children's Hospital, Oregon Health and Sciences University, Portland, Oregon, USA
Robert Butler
Affiliation:
Department of Cardiac Surgery, Doernbecher Children's Hospital, Oregon Health and Sciences University, Portland, Oregon, USA
Michael Silberbach
Affiliation:
Department of Cardiac Surgery, Doernbecher Children's Hospital, Oregon Health and Sciences University, Portland, Oregon, USA

Extract

Surgical treatment of hypoplastic left heart syndrome has generated substantial interest and attention amongst cardiac surgeons since the initial reports from Norwood and his colleagues in 1980.1,2 Initial efforts at most programmes were to create reproducible results, and mortality rates remained high at several institutions throughout the 1980s and 1990s. A recent multi-institutional review demonstrates that the hospital mortality still remains high in numerous centers at the current time.3 Nevertheless, several advances over recent years have led to improved outcomes, and in the best centers, hospital survival now approaches 90%. Survival in successful centers is claimed to relate to the ability of the team to help the patient balance the systemic and pulmonary flows of blood. This ability to balance flow has been enhanced, over recent years, by numerous contributions, including decreasing the size of shunt ordinarily used,4 the use of alpha blockade,5 the rapid deployment of extracorporeal membrane oxygenation,68 and various forms of ventilatory manipulation.

Type
Norwood Procedure and Staged Palliation
Copyright
© 2004 Cambridge University Press

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References

Norwood WI, Kirklin JK, Sanders SP. Hypoplastic left heart syndrome: experience with palliative surgery. Am J Cardiol 1980; 45: 8791.Google Scholar
Norwood WI, Lang P, Hansen DD. Physiologic repair of aortic atresia-hypoplastic left heart syndrome. N Engl J Med 1983; 308: 2326.Google Scholar
Jenkins KJ, Gauvreau K, Newburger JW, Spray TL, Moller JH, Iezzoni LI. Consensus-based method for risk adjustment for surgery for congenital heart disease. J Thorac Cardiovasc Surg 2002; 123: 110118.Google Scholar
Forbess JM, Cook N, Roth SJ, Serraf A, Mayer JE Jr, Jonas RA. Ten-year institutional experience with palliative surgery for hypoplastic left heart syndrome. Risk factors related to stage I mortality. Circulation 1995; 92: II262II266.Google Scholar
Tweddell JS, Hoffman GM, Fedderly RT, Berger S, Thomas JP Jr, Ghanayem NS, Kessel MW, Litwin SB. Phenoxybenzamine improves systemic oxygen delivery after the Norwood procedure. Ann Thorac Surg 1999; 67: 161168.Google Scholar
Drinkwater DC Jr, Aharon AS, Quisling SV, Dodd D, Reddy VS, Kavanaugh-McHugh A, Doyle T, Patel NR, Barr FE, Kambam JK, Graham TP, Chang PA. Modified Norwood operation for hypoplastic left heart syndrome. Ann Thorac Surg 2001; 72: 20812087.Google Scholar
Duncan BW, Ibrahim AE, Hraska V, del Nido PJ, Laussen PC, Wessel DL, Mayer JE Jr, Bower LK, Jonas RA. Use of rapid deployment extracorporeal membrane oxygenation for the resuscitation of pediatric patients with heart disease after cardiac arrest. J Thorac Cardiovasc Surg 1998; 116: 305311.Google Scholar
Pizarro C, Davis DA, Healy RM, Kerins PJ, Norwood WI. Is there a role for extracorporeal life support after stage I Norwood? Eur J Cardiothorac Surg 2001; 19: 294301.Google Scholar
Miller G, Tesman JR, Ramer JC, Baylen BG, Myers JL. Outcome after open-heart surgery in infants and children. J Child Neurol 1996; 11: 4953.Google Scholar
Mahle WT, Spray TL, Wernovsky G, Gaynor JW, Clark BJ III. Survival after reconstructive surgery for hypoplastic left heart syndrome: A 15-year experience from a single institution. Circulation 2000; 102 (19 Suppl 3): III136III141.Google Scholar
Mahle WT, Clancy RR, Moss EM, Gerdes M, Jobes DR, Wernovsky G. Neurodevelopmental outcome and lifestyle assessment in school-aged and adolescent children with hypoplastic left heart syndrome. Pediatrics 2000; 105: 10821089.Google Scholar
Rogers AJ, Trento A, Siewers RD, Griffith BP, Hardesty RL, Pahl E, Beerman LB, Fricker FJ, Fischer DR. Extracorporeal membrane oxygenation for post-cardiotomy cardiogenic shock in children. Ann Thorac Surg 1989; 47: 903906.Google Scholar
Rogers BT, Msall ME, Buck GM, Lyon NR, Norris MK, Roland JM, Gingell RL, Cleveland DC, Pieroni DR. Neurodevelopmental outcome of infants with hypoplastic left heart syndrome. J Pediatrics 1995; 126: 496498.Google Scholar
Rogers BT. Considering treatment options for infants with hypoplastic left heart syndrome. Acta Paediatr 2000; 89: 10291031.Google Scholar
Wernovsky G, Stiles KM, Gauvreau K, Gentles TL, duPlessis AJ, Bellinger DC, Walsh AZ, Burnett J, Jonas RA, Mayer JE Jr, Newburger JW. Cognitive development after the Fontan operation. Circulation 2000; 102: 883889.Google Scholar
Tsui S, Schultz J, Shen I, Ungerleider RM. Effects of hypoxemia on cerebral metabolism following exposure to deep hypothermic circulatory arrest. Ann Thorac Surg, in press.
Aharon AS, Drinkwater DC, Churchwell KB, Quisling SV, Reddy VS, Taylor M, Hix S, Christian KG, Pietsch JB, Deshpande JK, Kambam J, Graham TP, Chang PA. Extracorporeal membrane oxygenation in children after repair of congenital cardiac lesions. Ann Thorac Surg 2001; 72: 20952102.Google Scholar
Gaynor JW, Mahle WT, Cohen MI, Ittenbach RF, DeCampli WM, Steven JM, Nicolson SC, Spray TL. Risk factors for mortality after the Norwood procedure. Eur J Cardiothorac Surg 2002; 22: 8289.Google Scholar
Langley SM, Sheppard SV, Tsang VT, Monro JL, Lamb RK. When is extracorporeal life support worthwhile following repair of congential heart disease in children? Eur J Cardiothorac Surg 1998; 13: 520525.Google Scholar
Walters HL III, Hakimi M, Rice MD, Lyons JM, Whittlesey GC, Klein MD. Pediatric cardiac surgical ECMO: multivariate analysis of risk factors for hospital death. Ann Thorac Surg 1995; 60: 329337.Google Scholar
Weinhaus L, Canter C, Noetzel M, McAlister W, Spray TL. Extracorporeal membrane oxygenation for circulatory support after repair of congenital heart defects. Ann Thorac Surg 1989; 48: 206212.Google Scholar
Ziomek S, Harrell JE Jr, Fasules JW, Faulkner SC, Chipman CW, Moss M, Frazier E, Van Devanter SH. Extracorporeal membrane oxygenation for cardiac failure after congenital heart operation. Ann Thorac Surg 1992; 54: 861868.Google Scholar
Chai PJ, Williamson JA, Lodge AJ, Dagget CW, Scarborough JE, Meliones JN, Cheifetz IM, Jaggers JJ, Ungerleider RM. Effects of ischemia on pulmonary dysfunction after cardiopulmonary bypass. Ann Thorac Surg 1999; 67: 731735.Google Scholar
Darling EM, Kaemmer D, Lawson DS, Jaggers JJ, Ungerleider RM. Use of ECMO without the oxygenator to provide ventricular support after Norwood stage I procedures. Ann Thorac Surg 2001; 71: 735736.Google Scholar
Pigula FA, Nemoto EM, Griffith BP, Siewers RD. Regional low-flow perfusion provides cerebral circulatory support during neonatal aortic arch reconstruction. J Thorac Cardiovasc Surg 2000; 119: 331339.Google Scholar
Ungerleider RM. Role for deep hypothermic circulatory arrest during repair of heart defects in infants. J Thorac Cardiovasc Surg 2000; 120: 425426.Google Scholar
Langley SM, Chai PJ, Miller SE, Mault JR, Jaggers JJ, Tusi SS, Lodge AJ, Lefurgey A, Ungerleider RM. Intermittent perfusion protects the brain during deep hypothermic circulatory arrest. Ann Thorac Surg 1999; 68: 413.Google Scholar