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Holt-Oram syndrome and multiple ventricular septal defects: an association suggesting a possible genetic marker?

Published online by Cambridge University Press:  19 August 2008

Rolf G. Bennhagen  and
Samuel Menahem
Rolf G. Bennhagen
Affiliation:
Department of Cardiology, Royal Children's Hospital, Melbourne, Australia
Samuel Menahem*
Affiliation:
Department of Cardiology, Royal Children's Hospital, Melbourne, Australia
*
Professor S Menahem, Department of Cardiology, Royal Children's Hospital. Flemington Road, Parkville, Victoria. 3052, Australia. Tel: 61-3-9345 5715 Fax: 61-3-9345 6001.
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Abstract

A family is described where the father has the many skeletal, but none of the cardiac abnormalities associated with the Holt-Oram syndrome. His two daughters have similar skeletal anomalies, but with identical cardiac lesions, as does another patient, raising the possibility of an associated genetic marker.

Keywords

Multiple ventricular septal defectsHolt-Oram syndrome
Type
Brief Reports
Information
Cardiology in the Young , Volume 8 , Issue 1 , January 1998 , pp. 128 - 130
Copyright
Copyright © Cambridge University Press 1998

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References

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