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Management of fetal ductus arteriosus constriction with Digoxin and oxygen therapy

Published online by Cambridge University Press:  03 July 2020

Alina Z. Naqvi Open the ORCID record for Alina Z. Naqvi [Opens in a new window] ,
Susan M. Lanni  and
Joanna B. Rosenthal
Alina Z. Naqvi
Affiliation:
Virginia Commonwealth University School of Medicine, Richmond, VA, USA
Susan M. Lanni
Affiliation:
Division of Maternal Fetal Medicine, Department of OB/GYN, Virginia Commonwealth University, Richmond, VA, USA
Joanna B. Rosenthal*
Affiliation:
Division of Pediatric Cardiology, Department of Pediatrics, Children's Hospital of Richmond at Virginia Commonwealth University, Richmond, VA, USA
*
Address for correspondence: Joanna B. Rosenthal, MD, Children’s Pavilion, 1000 East Broad Street, Office #5-342, Richmond, VA23219, USA. Tel: (804) 628-4787; Fax: (804) 628-5858. E-mail: [email protected]
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Abstract

Constriction of the fetal ductus arteriosus is rare and usually attributed to medications or CHD. We describe a 24-year-old multigravida at 33 weeks 5 days gestation with echocardiographic findings of severe ductal constriction, a dilated, hypertrophied and hypocontractile right ventricle, and severe tricuspid regurgitation following BC powder® use. Treatment with Digoxin and oxygen resulted in a progressive 71% reduction in peak systolic ductal gradient, improved right ventricular function, and decreased tricuspid regurgitation.

Keywords

Constricted ductus arteriosusDigoxinoxygenantenatal
Type
Brief Report
Information
Cardiology in the Young , Volume 30 , Issue 8 , August 2020 , pp. 1183 - 1185
Copyright
© The Author(s), 2020. Published by Cambridge University Press

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