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Hemodynamic and angiographic findings following arterial switch repair for complete transposition

Published online by Cambridge University Press:  19 August 2008

Arun Srinivas
Affiliation:
From the Department of Cardiology, Royal Children's Hospital, Melbourne
Madathil Ranjit
Affiliation:
From the Department of Cardiology, Royal Children's Hospital, Melbourne
James L. Wilkinson*
Affiliation:
From the Department of Cardiology, Royal Children's Hospital, Melbourne
Tiow Goh
Affiliation:
From the Department of Cardiology, Royal Children's Hospital, Melbourne
Brian Edis
Affiliation:
From the Department of Cardiology, Royal Children's Hospital, Melbourne
Samuel Menahem
Affiliation:
From the Department of Cardiology, Royal Children's Hospital, Melbourne
Lance Fong
Affiliation:
From the Department of Cardiology, Royal Children's Hospital, Melbourne
Robert Weintraub
Affiliation:
From the Department of Cardiology, Royal Children's Hospital, Melbourne
*
Dr. James L. Wilkinson, Department of Cardiology, Royal Children's Hospital, Flemington Road, Parkville, Victoria 3052, Australia. Tel. 61-3-9345-5717; Fax. 61-3-9345-6001.

Abstract

The arterial switch operation is the treatment of choice for complete transposition, and for the Taussig-Bing anomaly, with good early and mid-term results. This retrospective study examined the findings obtained at routine follow-up cardiac catheterization after primary arterial switch repair. We catheterized 111 patients after a mean of 16.9 months after surgery. These included 67 patients with an intact ventricular septum, 33 with a ventricular septal defect, and 11 with the Taussig-Bing anomaly. Right ventricular pressures were mildly elevated (mean 33.9±10.2 mm Hg) in the overall group with a mean pressure ratio between right and left ventricles of 0.34±0.1. Of the patients 74% had gradients across the right ventricular outflow tract of under 20 mm Hg, while three (2.7%) had gradients over 30 mm Hg. A significant gradient across the left ventricular outflow tract occurred in one patient (0.9%), while significant neo-aortic stenosis was not seen. The neo-aortic root remained dilated, with mild aortic valvar incompetence being seen in 12%, with none having higher grades of regurgitation. Left ventricular ejection fraction was normal in all patients, while left ventricular end-diastolic pressure was elevated in 38%. Coronary arterial stenosis was not seen, but one patient (0.9%) had left ventricular apical dyskinesia. Overall, therefore, we conclude that cardiac hemodynamics and ventricular systolic function after primary arterial switch are good. Minor gradients to the pulmonary arteries, and mild neo-aortic valvar incompetence were commonly noted. Left ventricular end-diastolic pressure was elevated in over a third of the patients. These subclinical and subtle abnormalities warrant ongoing follow-up to determine their long-term significance.

Type
Original Manuscripts
Copyright
Copyright © Cambridge University Press 1996

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References

1.Jatene, AD, Fontes, VF, Paulista, PP, Souza, LCB, Neger, F, Galantier, M, Souza, JEMR. Anatomic correction of transposition of the great vessels. J Thorac Cardiovasc Surg 1976; 72: 364370.Google Scholar
2.Yacoub, MH, Radley-Smith, R, MacLaurin, R. Two-stage operation for anatomical correction of transposition of the great arteries with intact ventricular septum. Lancet 1977; 1: 12751278.Google Scholar
3.Stark, J. Transposition of the great arteries: which operation? Ann Thoracic Surg 1984; 38: 429431.Google Scholar
4.Fleming, WH. Why switch? J Thorac Cardiovasc Surg 1979; 78: 12.Google Scholar
5.Yacoub, MH. The case for anatomic correction of transposition of the great arteries. J Thorac Cardiovasc Surg 1979; 78: 36.CrossRefGoogle ScholarPubMed
6.Castaneda, AR, Norwood, WI, Jonas, RA, Colan, SD, Sanders, SP, Lang, P. Transposition of the great arteries and intact ventricular septum: Anatomical repair in the neonate. Ann Thorac Surg 1984; 38: 439443.Google Scholar
7.Radley-Smith, R, Yacoub, MH. One stage anatomic correction of simple transposition of the great arteries in neonates. Circulation 1984; 70 (Part 2): 11102.Google Scholar
8.Bical, O, Hazan, E, Lecompte, Y, Fermont, L, Karam, J, Jarreau, MM, Viet, TT, Sidi, D, Leca, F, Neveux, JY. Anatomic correction of transposition of the great arteries associated with ventricular septal defect: mid term results in 50 patients. Circulation 1984; 70: 891897.CrossRefGoogle Scholar
9.Quaegebeur, JM, Rohmer, J, Ottenkamp, J, Buis, T, Kirklin, JW, Blackstone, EH, Brown, AG. The arterial switch operation— an eight-year experience. J Thorac Cardiovasc Surg 1986; 92: 361384.Google Scholar
10.Idriss, FS, Ilbawi, MM, DeLeon, SY, Duffy, CE, Muster, AJ, Backer, CL, Berry, TE, Paul, MH. Transposition of the great arteries with intact ventricular septum Arterial switch in the first month of life. J Thorac Cardiovasc Surg 1988; 95: 255262.Google Scholar
11.Idriss, FS, Ilbawi, MN, DeLeon, SY, Duffy, CE, Muster, AJ, Berry, TE, Paul, MH. Arterial switch in simple and complex transposition of the great arteries. J Thorac Cardiovasc Surg 1988; 95: 2936.CrossRefGoogle ScholarPubMed
12.Wernovsky, G, Hougen, TJ, Walsh, EP, Scholler, GF, Colan, SD, Sanders, SP, Parness, IA, Keane, JF, Mayer, JE, Jonas, RA, Castaneda, AR, Lang, P. Midterm results after the arterial switch operation for transposition of the great arteries with intact ventricular septum: clinical, haemodynamic, echocardi-ographic and electrophysiologic data. Circulation 1988; 77: 13331344.CrossRefGoogle ScholarPubMed
13.Di Donate, RM, Wernovsky, G, Walsh, EP, Colan, SD, Lang, P, Wessel, DL, Jonas, RA, Mayer, JE, Castaneda, AR. Results of arterial switch operation for transposition of the great arteries with ventricular septal defect—surgical considerations and midterm follow-up. Circulation 1989; 80: 16891705.Google Scholar
14.Planche, C, Bruniaux, J, Lacour-Gayet, F, Kachaner, J, Binet, J, Sidi, D, Villain, E. Switch operation for transposition of the great arteries in neonates—a study of 120 patients. J Thorac Cardiovasc Surg 1988; 96: 354363.CrossRefGoogle ScholarPubMed
15.Brawn, WJ, Mee, RBB. Early results for anatomic correction of transposition of the great arteries and for double outlet right ventricle with subpulmonary ventricular septal defect. J Thorac Cardiovasc Surg 1988; 95: 230238.CrossRefGoogle ScholarPubMed
16.Castaneda, AR, Trusler, GA, Paul, MH, Blackstone, EH, Kirklin, JW. The early results of treatment of simple transposition in the current era. J Thorac Cardiovasc Surg 1988; 95: 1428.CrossRefGoogle ScholarPubMed
17.Norwood, WI, Dobell, AR, Freed, MD, Kirklin, JW, Blackstone, EH. Intermediate results of the arterial switch repair. A 20-institution study. J Thorac Cardiovasc Surg 1988; 96: 854863.CrossRefGoogle ScholarPubMed
18.Tsuda, E, Imakita, M, Yagihara, T, Ono, Y, Echigo, S, Takahashi, O, Kamiya, T. Late death after arterial switch operation for transposition of the great arteries. Am Heart J 1992; 124: 15511557.Google Scholar
19.Sellers, RD, Levy, MJ, Amplatz, K. Left retrograde cardioangi-ography in acquired cardiac disease. Technic, indications and interpretations in 700 cases. AmJCardiol 1964; 14:437458.CrossRefGoogle ScholarPubMed
20.Snow, JA, Baker, LD, Leshin, SJ. Validation of single plane cineangiographic determination of canine left ventricular volume II. Left ventricular dilatation. Fed Proc 1969; 28: 517.Google Scholar
21.Yang, SS, Bentivoglio, LG, Mavanahao, V, Goldbert, H. Cardiac chamber volume and left ventricular mass. In: From Cardiac Catheterisation Data to Haemodynamic Parameters. Third edition. F. A. Davis Company, 1988, pp 73113.Google Scholar
22.Roman, MJ, Deveraux, RB, Kramer-Fox, R, O'Loughlin, J. Two-dimensional echocardiographic aortic root dimensiions in normal children and adults. Am J Cardiol. 1989; 64: 507512CrossRefGoogle ScholarPubMed
23.Yacoub, MH, Bernhard, A, Radley-Smith, R, Lange, P, Sievers, H, Heintzen, P. Supravalvulvar pulmonary stenoses after anatomic correction of transposition of the great arteries: causes and prevention. Circulation 1982; 66(Suppl I): 11931197.Google Scholar
24.Lecompte, Y, Zannini, L, Hazan, E, Jarreau, MM, Bex, JP, Tu, TV, Neveux, JY. Anatomic correction of transposition of the great arteries. New technique without use of a prosthetic conduit. J Thorac Cardiovasc Surg 1981; 82: 629631.Google Scholar
25.Gleason, MM, Chin, AJ, Andrews, BA, Barber, G, Helton, JG, Murphy, JD, Norwood, WI. Two-dimensional and Doppler echocardiographic assessment of neonatal arterial repair for transposition of the great arteries. J Am Coll Cardiol 1989; 13: 13201328.CrossRefGoogle ScholarPubMed
26.Losay, J, Planche, C, Gerardin, B, Lacour-Gayet, F, Bruniaux, J, Kachaner, J. Midterm surgical results of arterial switch operation for transposition of the great arteries with intact septum. Circulation 1990;82 (Suppl IV): IV146IV150.Google Scholar
27.Arensman, FW, Radley-Smith, R, Yacoub, MH, Lange, P, Bernhard, A, Sievers, HH, Heintzen, P. Catheter evaluation of left ventricular shape and function one or more years after anatomic correction of transposition of the great arteries. Am J Cardiol 1983; 52: 10791083.CrossRefGoogle ScholarPubMed
28.Yacoub, MH, Bernhard, A, Lange, P, Radley-Smith, R, Keck, E, Stephen, E, Heintzen, P. Clinical and haemodynamic results of the two-stage anatomic correction of simple transposition of the great arteries. Circulation 1980; 62 (Suppl I): 11901196.Google ScholarPubMed
29.Lange, PE, Sievers, HH, Onnasch, DGW, Yacoub, MH, Bernhard, A, Heintzen, PH. Up to 7 years of followup after two-stage anatomic correction of simple transposition of the great arteries. Circulation 1986; 74 (Suppl I): 147152.Google ScholarPubMed
30.Sievers, HH, Lange, PE, Onnasch, DGW, Radley-Smith, R, Yacoub, MH, Heintzen, PH, Regensburger, D, Bernhard, A. Influence of the two-stage anatomic correction of simple transposition of the great arteries on left ventricular function. AmJ Cardiol 1985; 56: 514519.CrossRefGoogle ScholarPubMed
31.Colan, SD, Trowitzsch, E, Wernovsky, G, Sholler, GF, Sanders, SP, Castaneda, AR. Myocardial performance after arterial switch operation for transposition of the great arteries with intact ventricular septum. Circulation 1988; 78: 132141.Google Scholar
32.Borow, KM, Arensman, FW, Webb, C, Radley-Smith, R, Yacoub, MH. Assessment of left ventricular contractile state after anatomic correction of transposition of the great arteries. Circulation 1984; 69: 106112.CrossRefGoogle ScholarPubMed
33.Sievers, HH, Lange, PE, Arensman, FW, Radley-Smith, R, Yacoub, MH, Harms, D, Heintzen, PH, Bernhard, A. Influence of two-stage anatomic correction on size and distensibility of the anatomic pulmonary / functional aortic root in patients with simple transposition of the great arteries. Circulation 1984; 70: 202208.Google Scholar
34.Arensman, FW, Sievers, HH, Lange, P, Radley-Smith, R, Bernhard, A, Heintzen, P, Yacoub, MH. Assessment of coronary and aortic anastomosis after anatomic correction of transposition of the great arteries. J Thorac Cardiovasc Surg 1985; 90: 597604.Google Scholar