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Fibromuscular dysplasia as the substrate for systemic and pulmonary hypertension in the setting of Moya-Moya disease

Published online by Cambridge University Press:  20 September 2006

Phalla Ou ,
Peggy Dupont  and
Damien Bonnet
Phalla Ou
Affiliation:
Cardiologie Pédiatrique, Hôpital Necker-Enfants Malades, AP-HP, Paris, France
Peggy Dupont
Affiliation:
Cardiologie Pédiatrique, Hôpital Necker-Enfants Malades, AP-HP, Paris, France
Damien Bonnet
Affiliation:
Cardiologie Pédiatrique, Hôpital Necker-Enfants Malades, AP-HP, Paris, France
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Abstract

We report the first case, to the best of our knowledge, of a child with the unusual association of Moya-Moya disease and both systemic and pulmonary hypertension. Histological examination revealed fibromuscular dysplasia as the common denominator for a diffuse arteriopathy.

Keywords

Pulmonary arterial stenosisrenal arterial stenosiscerebrovascular pathology
Type
Brief Report
Information
Cardiology in the Young , Volume 16 , Issue 5 , October 2006 , pp. 495 - 497
Copyright
© 2006 Cambridge University Press

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References

Natori Y, Ikezaki K, Matsushima T, Fukui M. “Angiographic moyamoya” its definition, classification, and therapy. Clin Neurol Neurosurg 1997; 99 (Suppl 2): S168–S172.Google Scholar
Choi Y, Kang BC, Kim KJ, et al. Renovascular hypertension in children with moyamoya disease. J Pediatr 1997; 131: 258–263.Google Scholar
Kapusta L, Daniels O, Renier WO. Moya-Moya syndrome and primary pulmonary hypertension in childhood. Neuropediatrics 1990; 21: 162–163.Google Scholar
de Vries RR, Nikkels PG, van der Laag J, Broere G, Braun KP. Moyamoya and extracranial vascular involvement: fibromuscular dysplasia? A report of two children. Neuropediatrics 2003; 34: 318–321.Google Scholar
Fukuhara H, Kitayama H, Yokoyama T, Shirotani H. Thromboembolic pulmonary hypertension due to disseminated fibromuscular dysplasia. Pediatr Cardiol 1996; 17: 340–345.Google Scholar
Slovut DP, Olin JW. Fibromuscular dysplasia. N Engl J Med 2004; 350: 1862–1871.Google Scholar
Sang CN, Whelton PK, Hamper UM, et al. Etiologic factors in renovascular fibromuscular dysplasia. A case-control study. Hypertension 1989; 14: 472–479.Google Scholar
Pannier-Moreau I, Grimbert P, Fiquet-Kempf B, et al. Possible familial origin of multifocal renal artery fibromuscular dysplasia. J Hypertens 1997; 15: 1797–1801.Google Scholar
Bofinger A, Hawley C, Fisher P, Daunt N, Stowasser M, Gordon R. Polymorphisms of the renin-angiotensin system in patients with multifocal renal arterial fibromuscular dysplasia. J Hum Hypertens 2001; 15: 185–190.Google Scholar
Isono M, Ishii K, Kamida T, Inoue R, Fujiki M, Kobayashi H. Long-term outcomes of pediatric moyamoya disease treated by encephalo-duro-arterio-synangiosis. Pediatr Neurosurg 2002; 36: 14–21.Google Scholar