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The Autonomic Reflex Screen in Healthy Participants from Southwestern Ontario

Published online by Cambridge University Press:  23 September 2014

Colleen T. Ives ,
Michael J. Berger  and
Kurt Kimpinski
Colleen T. Ives
Affiliation:
Department of Clinical Neurological Sciences, University Hospital, London Health Sciences Centre, London, Ontario, Canada
Michael J. Berger
Affiliation:
Schulich School of Medicine & Dentistry, Western University, London, Ontario, Canada
Kurt Kimpinski*
Affiliation:
Department of Clinical Neurological Sciences, University Hospital, London Health Sciences Centre, London, Ontario, Canada Schulich School of Medicine & Dentistry, Western University, London, Ontario, Canada
*
Rm. C7-131, University Hospital, London Health Sciences Centre, 339 Windermere Road, London, Ontario, N6A 5A5, Canada. Email: [email protected].
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Abstract

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Background:

The autonomic reflex screen (ARS) is a composite of well-defined tests of various autonomic domains and is an essential part of the diagnosis of autonomic disorders. Institutional and regional differences exist and necessitate the ongoing development of control values for the ARS. Here we present data obtained from healthy participants from Southwestern Ontario.

Methods:

A total of 121 healthy individuals underwent quantitative sudomotor axon reflex testing (QSART), heart rate response to deep breathing (HRDB), and Valsalva maneuver using standard protocols as part of the ARS.

Results:

Sweat volumes obtained during QSART are presented by site (forearm, proximal leg, distal leg and foot) and by gender. Data is expressed as the mean sweat volume per site with the associated 2.5th, 5th and 95th percentiles. Data for males and females is also stratified by age group (14-25, 26-40 and 41-76 years). Measurements of cardiovagal parasympathetic function including HRDB and Valsalva ratio are stratified by age group (14-25, 26- 40 and 41-76 years). Data is expressed as the mean with associated percentiles (2.5, 5, 95 and 97.5 percentiles).

Conclusions:

The current manuscript provides control data for the various components of the ARS to aid in the diagnosis of autonomic disorders.

Résumé

RÉSUMÉ Contexte:

La grille de dépistage des réflexes autonomes (GDRA) est composée de tests bien définis portant sur des fonctions autonomes variées et elle est une partie essentielle du diagnostic des maladies du système nerveux autonome. Il existe des différences institutionnelles et régionales, de là la nécessité d'établir des valeurs-témoins pour la GDRA. Nous présentons les données obtenues chez des sujets sains du sud-ouest de l'Ontario.

Méthode:

Un protocole standard de test quantitatif de l'axone réflexe sudomoteur (QARS), de la réponse du rythme cardiaque à la respiration profonde (RCRP) et de la manœuvre de Valsalva a été utilisé chez 121 individus en bonne santé dans le cadre de la GDRA.

Résultats:

Les volumes de sueur obtenus pendant le QARS sont présentés par région (avant-bras, région proximale de la jambe, région distale de la jambe et pied) et par sexe. Les données rapportées sont le volume de sueur moyen par région ainsi que les 2,5e, 5e et 95e percentiles. Les données pour les hommes et pour les femmes sont également stratifiées par groupe d'âge (14 à 25 ans, 26 à 40 ans et 41 à 76 ans). Les mesures de la fonction parasympathique cardiaque incluant la RCRP et le rapport de Valsalva sont également rapportés pour les mêmes groupes d'âge ainsi que la moyenne pour les percentiles 2,5e, 5e, 95e et 97,5e percentiles.

Conclusions:

Cet article présente des données témoins pour les différentes composantes de la GDRA en vue de faciliter le diagnostic des maladies du système nerveux autonome.

Type
Original Article
Information
Canadian Journal of Neurological Sciences , Volume 40 , Issue 6 , November 2013 , pp. 848 - 853
Copyright
Copyright © The Canadian Journal of Neurological 2013

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