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Origin of error signals during cerebellar learning of motor sequences

Published online by Cambridge University Press:  30 August 2019

Michel Dufossé
Affiliation:
Laboratoire Creare, UPMC, cp 23, 75 252 Paris cedex 05, [email protected]
Arthur Kaladjian
Affiliation:
Laboratoire Creare, UPMC, cp 23, 75 252 Paris cedex 05, [email protected]
Philippe Grandguillaume
Affiliation:
Laboratoire Creare, UPMC, cp 23, 75 252 Paris cedex 05, [email protected]

Abstract

Prefrontal cerebral areas project to Purkinje cells, located in the most lateral part of the cerebellum, via mossy and climbing fibers. The latter olivary error signals reflect the attentional load of the prefrontal cortex. At the cerebral level, LTP-LTD plasticity allows these Purkinje cells to adaptively reinforce the active pyramidal cells involved in the motor sequence.

Type
Open Peer Commentary
Copyright
1997 Cambridge University Press

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