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Genes can disconnect the social brain in more than one way

Published online by Cambridge University Press:  15 June 2005

André Aleman*
Affiliation:
Rudolf Magnus Institute for Neurosciences, Department of Psychiatry, A01.126 University Medical Center, 3584CXUtrecht, The Netherlands
René S. Kahn*
Affiliation:
Rudolf Magnus Institute for Neurosciences, Department of Psychiatry, A01.126 University Medical Center, 3584CXUtrecht, The Netherlands

Abstract:

Burns proposes an intriguing hypothesis by suggesting that the “schizophrenia genes” might not be regulatory genes themselves, but rather closely associated with regulatory genes directly involved in the proper growth of the social brain. We point out that this account would benefit from incorporating the effects of localized lesions and aberrant hemispheric asymmetry on cortical connectivity underlying the social brain. In addition, we argue that the evolutionary framework is superfluous.

Type
Open Peer Commentary
Copyright
Copyright © Cambridge University Press 2004

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