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Steps to a neurochemistry of personality

Published online by Cambridge University Press:  01 June 1999

Andrew D. Lawrence ,
Matthias J. Koepp ,
Roger N. Gunn ,
Vincent J. Cunningham  and
Paul M. Grasby
Andrew D. Lawrence
Affiliation:
MRC Cyclotron Unit, Division of Neuroscience, Imperial College School of Medicine, Hammersmith Campus, London W12 0NN, United [email protected] Departments of Sensorimotor Systems and Psychological Medicine, Division of Neuroscience, Imperial College School of Medicine, Hammersmith Campus, London W12 0NN, United [email protected]
Matthias J. Koepp
Affiliation:
MRC Cyclotron Unit, Division of Neuroscience, Imperial College School of Medicine, Hammersmith Campus, London W12 0NN, United [email protected] Departments of Sensorimotor Systems and Psychological Medicine, Division of Neuroscience, Imperial College School of Medicine, Hammersmith Campus, London W12 0NN, United [email protected]
Roger N. Gunn
Affiliation:
MRC Cyclotron Unit, Division of Neuroscience, Imperial College School of Medicine, Hammersmith Campus, London W12 0NN, United [email protected]
Vincent J. Cunningham
Affiliation:
MRC Cyclotron Unit, Division of Neuroscience, Imperial College School of Medicine, Hammersmith Campus, London W12 0NN, United [email protected]
Paul M. Grasby
Affiliation:
MRC Cyclotron Unit, Division of Neuroscience, Imperial College School of Medicine, Hammersmith Campus, London W12 0NN, United [email protected] Departments of Sensorimotor Systems and Psychological Medicine, Division of Neuroscience, Imperial College School of Medicine, Hammersmith Campus, London W12 0NN, United [email protected]
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Abstract

Depue & Collins's (D&C's) work relies on extrapolation from data obtained through studies in experimental animals, and needs support from studies of the role of dopamine (DA) neurotransmission in human behaviour. Here we review evidence from two sources: (1) studies of patients with Parkinson's disease and (2) positron emission tomography (PET) studies of DA neurotransmission, which we believe lend support to Depue & Collins's theory, and which can potentially form the basis for a true neurochemistry of personality.

Type
Open Peer Commentary
Information
Behavioral and Brain Sciences , Volume 22 , Issue 3 , June 1999 , pp. 528 - 529
Copyright
© 1999 Cambridge University Press

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