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Plasma Protein Variability in MZ Twins

Published online by Cambridge University Press:  01 August 2014

M. Milani-Comparetti  and
F. Saccucci
M. Milani-Comparetti*
Affiliation:
Institute of Biology and Genetics, Medical School, University of Ancona, Italy
F. Saccucci
Affiliation:
Institute of Biology and Genetics, Medical School, University of Ancona, Italy
*
Institute of Biology and Genetics, Medical School, University of Ancona, 60100 Ancona, Italy

Abstract

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A previous study had shown that only MZ twins are easily exchanged by trained police dogs. This is certainly due to the superimposability of the biochemical basis of body scent. A different approach has now been tried, based on plasma protein fractionating procedures. A pilot study has shown that PolyAcrilamide Gel Electrophoresis (PAGE) results, as expected, in widely different patterns only in DZ twin pairs. Plasma specimens from a sample of 55 supposedly MZ twin pairs were analysed by PAGE. The substantial superimposability of MZ cotwin patterns was confirmed. Analysis of the different fractions indicates the extent of environmental variability. Application to zygosity determination is suggested.

Type
5. Twin Studies in Human Genetics
Information
Acta geneticae medicae et gemellologiae: twin research , Volume 25 , Issue 1 , January 1976 , pp. 154 - 156
Copyright
Copyright © The International Society for Twin Studies 1976

References

REFERENCES

Gedda, L., Casa, D., Milani-Comparetti, M. 1971. Twin zygosity diagnosis: Experiments with bloodhounds. Excerpta Med. Int. Congr. Ser., 233: 74.Google Scholar
Gedda, L., Milani-Comparetti, M., D'Alessandro, E. 1974. « Equivocalness » and other empirical methods in zygosity assessment. Proc. 1st Int. Congr. Twin Studies, Rome. Acta Genet. Med. Gemellol. (Roma), 25: 117–120.Google Scholar
Milani-Comparetti, M., Sega, E., Isabella, F., Citro, G., Britti, F. 1975. Genetic and environmental variability of human plasma protein fractions: pilot study on a twin sample by disc electrophoresis on polyacrylamide gel. Biochem. Exp. Biol., XI, 3: 267–270.Google Scholar
Sega, E., Isabella, F., Citro, G. 1971. Elettroforesi a disco su gel di acrilammide. Nota I: Considerazioni preliminari su alcuni patterns normali e patologici. Boll. 1st. Sieroter. Milanese, 50: 422.Google Scholar
Sega, E., Minetti, M., Petrucci, T. 1973. Elettroforesi a disco su gel di poliacrilamide. Nota II: Variabilità dei « patterns » del siero di pazienti con M. di Hodgldn nei confronti di quelli di individui normali. Boll. 1st. Sieroter. Milanese, 52: 242.Google Scholar