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Metabolic Research in Monozygotic Twins with Diabetes Mellitus: Progress Report*
Published online by Cambridge University Press: 01 August 2014
Abstract
An intravenous and oral glucose tolerance test and an intravenous tolbutamide test have been performed in 11 MZ twin pairs, discordant for diabetes mellitus. Blood sugar, immunoreactive insulin, and free fatty acids were determined. The research aimed at finding out whether prediabetic subjects may show any characteristic parameter which could be suggestive of the hereditary disposition. Three MZ twins of juvenile diabetics showed a normal blood glucose, immunoreactive insulin, and free fatty acids during the glucose and tolbutamide loads within a maximum of 10 years observation.
- Type
- 7. Twin Studies in Medical and Clinical Genetics
- Information
- Acta geneticae medicae et gemellologiae: twin research , Volume 25 , Issue 1 , January 1976 , pp. 281 - 288
- Copyright
- Copyright © The International Society for Twin Studies 1976
Footnotes
The investigations have been supported by the Deutsche Forschungs-Gemeinschaft.