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A Case-Control Study of Maternal Gestational Weight Gain and Newborn Birthweight and Birthlength in Twin Pregnancies Complicated by Preeclampsia

Published online by Cambridge University Press:  06 September 2016

B. Luke ,
L. Keith ,
J.A. Lopez-Zeno ,
F.R. Witter  and
E. Saquil
B. Luke
Affiliation:
Division of Maternal-Fetal Medicine, Department of Gynecology and Obstetrics, Johns Hopkins University School of Medicine, Baltimore, Maryland Center for Study of Multiple Births, Chicago Section of Reproductive and Perinatal Epidemiology, Department of Obstetrics and Gynecology, Rush Medical College, Rush-Presbyterian-St. Luke’s Medical Center, Chicago, Illinois
L. Keith*
Affiliation:
Department of Obstetrics and Gynecology, Northwestern University Medical School and Prentice Women’s Hospital of Northwestern Memorial Hospital, Chicago Center for Study of Multiple Births, Chicago Jeanette Kennelly Kroch Center for Twin Studies, Northwestern Memorial Hospital, Chicago
J.A. Lopez-Zeno
Affiliation:
Department of Obstetrics and Gynecology, Northwestern University Medical School and Prentice Women’s Hospital of Northwestern Memorial Hospital, Chicago Department of Obstetrics and Gynecology, The George Washington University School of Medicine, Washington, D.C.
F.R. Witter
Affiliation:
Division of Maternal-Fetal Medicine, Department of Gynecology and Obstetrics, Johns Hopkins University School of Medicine, Baltimore, Maryland
E. Saquil
Affiliation:
Center for Study of Multiple Births, Chicago
*
Northwestern University Medical School, Department of Obstetrics and Gynecology, 333 East Superior Street, Suite 464, Chicago, IL 60611, USA

Abstract

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To evaluate the influence of rate of gestational weight gain on newborn birthweight and birthlength in twin gestations complicated by preeclampsia, 74 cases of preeclampsia in twin pregnancy were matched to 148 non-preeclamptic twin controls for maternal race, height, pregravid weight, age and length of gestation. Total weight gain was significantly higher for all cases versus controls and for mild cases versus controls. However, the rate of early weight gain was lower for severe cases and severe cases with thrombocytopenia compared to their controls. Mean birthweight and birthlength did not differ between cases and controls, although the proportion with birthlength below the 10th percentile was significantly higher among cases than controls. In addition, the proportion of birthweights and birthlengths < 10th percentile was significantly higher among cases than controls. These findings suggest that inadequate early weight gain in twin gestations complicated by preeclampsia results in retarded birthlength and birthweight. The implication of these findings are discussed.

Keywords

Gestational Weight gainPreeclampsiaTwins
Type
Research Article
Information
Acta geneticae medicae et gemellologiae: twin research , Volume 42 , Issue 1 , 1993 , pp. 7 - 15
Copyright
Copyright © The International Society for Twin Studies 1993

References

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