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Alcohol Consumption in Relation to Factors Associated with Ischemic Heart Disease - A Cotwin Control Study

Published online by Cambridge University Press:  01 August 2014

Marten Myrhed*
Affiliation:
Department of Medicine, Serafimer Hospital, and Department of Environmental Hygiene, Karolinska Institute, Stockholm, Sweden
Birgitta Floderus
Affiliation:
Department of Medicine, Serafimer Hospital, and Department of Environmental Hygiene, Karolinska Institute, Stockholm, Sweden
*
Department of Clinical Alcohol and Drug Research, Karolinska Hospital, S-104 01 Stockholm 60, Sweden

Abstract

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Moderately alcohol-discordant male twin pairs, aged 45-65 years, have been examined with respect to ischemic heart disease (IHD) and associated factors. No conclusion can yet be drawn with regard to manifest or subclinical IHD, while significant disparities were found with regard to systolic and diastolic blood pressures, high cigarette consumption, hyperglycemia, and serum cholesterol; the greater number of findings of pathological values were found in the high alcohol-consumption as compared to the low alcohol-consumption cotwins. These findings offer a possible explanation for the increased number of reports showing a connection between high consumption of alcohol and occurrence of ischemic heart disease.

Type
4. The Cotwin Method and Experimental Science
Copyright
Copyright © The International Society for Twin Studies 1976

References

REFERENCES

Blackburn, H., Keys, A., Simonson, E., Rautaharju, P., Punsar, S. 1960. The electrocardiogram in population studies. A classification system. Circulation, 21: 1160.CrossRefGoogle ScholarPubMed
Cederlöf, R. 1966. The Twin Method in Epidemiological Studies on Chronic Diseases. Stockholm: Essclte.Google Scholar
Cederlöf, R., Floderus, B., Friberg, L. 1970. The Swedish Twin registry. Past and future use. Acta Genet. Med. Gemellol. (Roma), 19: 351.Google Scholar
Epstein, F.H. 1964. Hereditary aspects of coronary heart disease. Am. Heart J., 67: 445.Google Scholar
Epstein, F.H. 1965. The epidemiology of coronary heart disease. A review. J. Chronic Dis., 18: 735.CrossRefGoogle ScholarPubMed
Lundman, T. 1973. Genetic Predisposition of Ischaemic Heart Disease - Twin Studies. Early Phases of Coronary Heart Disease [p. 186]. Stockholm: Skandia Intern. Symposia. Nord. Bokh. Google Scholar
Myrhed, M. 1974. Alcohol consumption in relation to factors associated with ischemic heart disease. A co-twin control study. Acta Med. Scand. [Suppl.], 567.Google Scholar
Pell, S., D'Alonzo, C.A. 1973. A five-year mortality study of alcoholics. J. Occup. Med., 15: 120.Google Scholar
Rose, G. 1964. Familial patterns in ischaemic heart disease. Br. J. Prev. Soc. Med., 18: 75.Google Scholar
Russek, H.I.,Zohman, B.L. 1958. Relative significance of heredity, diet and occupational stress in coronary heart disease of young adults. Based on an analysis of 100 patients between the ages of 25 and 40 years and a similar group of 100 normal control subjects. Am. J. Med. Sci., 235: 266.CrossRefGoogle Scholar
Schmidt, W., de Lint, J. 1972. Causes of death of alcoholics. Q. J. Stud. Alcohol, 33: 171.Google Scholar
Sundby, P. 1967. Alcoholism and Mortality. Oslo: Universitetsförlaget.Google Scholar
Thomas, C.B. 1958. Familial and epidemiologic aspects of coronary disease and hypertension. J. Chronic. Dis., 7: 199.Google Scholar
Thomas, C.B. 1959. Familial patterns in hypertension and coronary heart disease. Circulation, 20: 25.Google Scholar
Wilhelmsen, L., Wedel, H., Tibblin, G. 1973. Multivariate analysis of risk factors for coronary heart disease. Circulation, 48: 950.Google Scholar