Brain Disorders in Critical Illness: Mechanisms, Diagnosis, and Treatment

doi:10.1017/CBO9781139248822

Brain Disorders in Critical Illness

Mechanisms, Diagnosis, and Treatment

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Patel, Mayur B. Jackson, James C. Morandi, Alessandro Girard, Timothy D. Hughes, Christopher G. Thompson, Jennifer L. Kiehl, Amy L. Elstad, Mark R. Wasserstein, Mitzi L. Goodman, Richard B. Beckham, Jean C. Chandrasekhar, Rameela Dittus, Robert S. Ely, E. Wesley and Pandharipande, Pratik P. 2016. Incidence and Risk Factors for Intensive Care Unit–related Post-traumatic Stress Disorder in Veterans and Civilians. American Journal of Respiratory and Critical Care Medicine, Vol. 193, Issue. 12, p. 1373.

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Cao, Xi Hogan, Anna and Moore, Eric 2019. Rapid Separation of Organophosphate Pesticides using Micellar Electrokinetic Chromatography and Short‐end Injection, . Journal of Forensic Sciences, Vol. 64, Issue. 4, p. 1213.

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Slooter, Arjen J. C. Otte, Wim M. Devlin, John W. Arora, Rakesh C. Bleck, Thomas P. Claassen, Jan Duprey, Matthew S. Ely, E. Wesley Kaplan, Peter W. Latronico, Nicola Morandi, Alessandro Neufeld, Karin J. Sharshar, Tarek MacLullich, Alasdair M. J. and Stevens, Robert D. 2020. Updated nomenclature of delirium and acute encephalopathy: statement of ten Societies. Intensive Care Medicine, Vol. 46, Issue. 5, p. 1020.

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Ramineni, Anil and Dangayach, Neha 2021. Mount Sinai Expert Guides. p. 241.

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Edited by Robert D. Stevens, The Johns Hopkins University School of Medicine, Tarek Sharshar, Raymond Poincaré Hospital, Paris, E. Wesley Ely, Vanderbilt University, Tennessee

Publisher:: Cambridge University Press
Online publication date:: October 2013
Print publication year:: 2013
Online ISBN:: 9781139248822
DOI:: https://doi.org/10.1017/CBO9781139248822

Subjects:: Anesthesia, Intensive Care, Pain Management, Neurology and Clinical Neuroscience, Medicine

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Brain dysfunction is a major clinical problem in intensive care, with potentially debilitating long-term consequences for post-ICU patients of any age. The resulting extended length of stay in the ICU and post-discharge cognitive dysfunction are now recognized as major healthcare burdens. This comprehensive clinical text provides intensivists and neurologists with a practical review of the pathophysiology of brain dysfunction and a thorough account of the diagnostic and therapeutic options available. Initial sections review the epidemiology, outcomes, relevant behavioral neurology and biological mechanisms of brain dysfunction. Subsequent sections evaluate the available diagnostic options and preventative and therapeutic interventions, with a final section on clinical encephalopathy syndromes encountered in the ICU. Each chapter is rich in illustrations, with an executive summary and a helpful glossary of terms. Brain Disorders in Critical Illness is a seminal reference for all physicians and neuroscientists interested in the care and outcome of severely ill patients.

'The chapters are concise, well written, and well organized … This very strong and well-referenced basic science text covers a broad range of topics including neuroanatomy, neurophysiology, and biochemistry, and delivers a solid foundation that clinicians can translate to an increased understanding of brain dysfunction at bedside.'

Source: Canadian Journal of Anesthesia

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