from Section E - Fertility and Reproduction
Published online by Cambridge University Press: 22 December 2022
Pubertal suppression is a treatment option for minors with gender incongruity and dysphoria and is recommended by the World Professional Association for Transgender Health (WPATH) and Endocrine Society. Unfortunately, there are limited data regarding the effect of gonadotropin-releasing hormone (GnRH) agonists, or “puberty blockers,” on future fertility in transgender and nonbinary youth. In this chapter, we will describe the potential consequences of GnRH agonist use for puberty blockade on later fertility, fertility preservation options depending on sex assigned at birth, and ethical implications in fertility preservation counseling before prescribing puberty blockers in adolescents.
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