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Chapter 26 - Fertility Maintenance for Trans Women

from Section E - Fertility and Reproduction

Published online by Cambridge University Press:  22 December 2022

Mick van Trotsenburg
Affiliation:
Sigmund Freud PrivatUniversität, Wien
Rixt A. C. Luikenaar
Affiliation:
Rebirth Health Center, Utah
Maria Cristina Meriggiola
Affiliation:
Università di Bologna
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Summary

This chapter reviews fertility preservation options and procedures for trans female persons, since gender-affirming hormone therapy has a clear negative impact on steroidogenesis and spermatogenesis. Established urological procedures for fertility preservation can be applied early during the transition process to retrieve and cryopreserve sperm. Experimental strategies may be applicable at later stages.

Type
Chapter
Information
Context, Principles and Practice of TransGynecology
Managing Transgender Patients in ObGyn Practice
, pp. 194 - 200
Publisher: Cambridge University Press
Print publication year: 2022

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References

Cartaya, J, Lopez, X. Gender dysphoria in youth: a review of recent literature. Curr Opin Endocrinol Diabetes Obes 2018;25:4448.Google Scholar
Chen, D, Simons, L, Johnson, EK, Lockart, BA, Finlayson, C. Fertility preservation for transgender adolescents. J Adolesc Health 2017;61:120123.CrossRefGoogle ScholarPubMed
Jones, CA, Reiter, L, Greenblatt, E. Fertility preservation in transgender patients. Int J Transgenderism 2016;17:7682.CrossRefGoogle Scholar
Millar, A, Kim, BHK, Livne-Segev, D, et al. Attitudes, knowledge and beliefs regarding fertility preservation among people of transgendered experience: preliminary results. Can J Diabetes 2015;39:536.Google Scholar
Nahata, L, Tishelman, AC, Caltabellotta, NM, Quinn, GP. Low fertility preservation utilization among transgender youth. J Adolesc Health 2017;61:4044.Google Scholar
Nieder, TO, Strauß, B. S3-Leitlinie zur Diagnostik, Beratung und Behandlung im Kontext von Geschlechtsinkongruenz, Geschlechtsdysphorie und Trans-Gesundheit: Hintergrund, Methode und zentrale Empfehlungen. Zeitschr Sexualforsch 2019;32:7079.Google Scholar
World Professional Association for Transgender Health (WPATH). Standards of Care for the Health of Transsexual, Transgender, and Gender Nonconforming People, 7th Version. Minneapolis, MN: WPATH, 2011.Google Scholar
Hembree, WC, Cohen-Kettenis, P, Delemarre-van de Waal, HA, et al. Endocrine treatment of transsexual persons: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab 2009;94(9):31323154. https://doi.org/10.1210/jc.2009-0345CrossRefGoogle ScholarPubMed
Lai, TC, Davies, C, Robinson, K, et al. Effective fertility counselling for transgender adolescents: a qualitative study of clinican attitudes and practices. BMJOpen 2020;2020:043237.Google Scholar
Mitu, K. Transgender reproductive choice and fertility preservation. AMA J Ethics 2016;18:11191125.Google ScholarPubMed
Mattawanon, N, Spencer, JB, Schirmer, DA, Tangpricha, V. Fertility preservation options in transgender people: a review. Rev Endocr Metab Disord 2018;19:231242.Google Scholar
James-Abra, S, Tarasoff, LA, Green, D, et al. Trans people’s experiences with assisted reproduction services: A qualitative study. Hum Reprod 2015;30:13651374.CrossRefGoogle ScholarPubMed
Kosenko, K, Rintamaki, L, Raney, S, Maness, K. Transgender patient perceptions of stigma in health care contexts. Med Care 2013;51:819822.Google Scholar
Goosens, E, Jahnukainen, K, Mitchell, RT, et al. Fertility preservation in boys: recent developments and new insights. Hum Reprod Open 2020;2020(3):hoaa016.CrossRefGoogle Scholar
Neuhaus, N, Schlatt, St. Stem cell-based options to preserve male fertility. Science 2019;363(6433):12831284.Google Scholar
Brik, T, Vrouenraets, LJJJ, Schagen, SEE, et al. Use of fertility preservation among a cohort of transgirls in the Netherlands. J Adolesc Health 2019;64:589593.Google Scholar
Strang, JF, Jarin, J, Call, D, et al. Transgender youth fertility attitudes questionnaire: measure development in nonautistic and autistic transgender youth and their parents. J Adolesc Health 2018;62:128135.CrossRefGoogle ScholarPubMed
Payne, JG, Erbenius, T. Conceptions of transgender parenthood in fertility care and family planning in Sweden: from reproductive rights to concrete practices. Anthropol Med 2018;25:329343.Google Scholar
Auer, MK, Fuss, J, Nieder, TO, et al. Desire to have children among transgender people in Germany: a cross-sectional multi-center study. J Sex Med 2018;15:757767.Google Scholar
Riggs, DW, Bartholomaeus, C. Fertility preservation decision making amongst Australian transgender and non-binary adults. Reprod Health 2018;15:181.CrossRefGoogle ScholarPubMed
Goldman, RH, Kaser, DJ, Missmer, SA, et al. Fertility treatment for the transgender community: a public opinion study. J Assist Reprod Genet 2017;34:14571467.CrossRefGoogle ScholarPubMed
Wakefield, BW, Boguszewski, K, Cheney, D, Taylor, J. Trends in fertility preservation for transgender adolescents and young adults at an academic referral center. J Adolesc Health 2018;62:S41.Google Scholar
Schneider, F, Neuhaus, N, Wistuba, J, et al. Testicular functions and clinical characterization of patients with gender dysphoria (GD) undergoing sex reassignment surgery (SRS). J Sex Med 2015;12:21902200.Google Scholar
Schneider, F, Redmann, K, Wistuba, J, et al. Comparison of enzymatic digestion and mechanical dissociation of human testicular tissue. Fertil Steril 2015;104(2):302311.Google Scholar
World Health Organization. WHO Laboratory Manual for the Examination and Processing of Human Semen. Geneva: WHO, 2021. www.who.int/publications/i/item/9789240030787.Google Scholar
Krege, S, Eckoldt, F, Richter-Unruh, A, et al. Variations of sex development: the first German interdisciplinary consensus paper. J Pediatr Urol 2019;15:114123.Google Scholar
Meriggiola, MC, Berra, M. Safety of hormonal treatment in transgenders. Reprod Endocrinol 2013;20:565569.Google ScholarPubMed
Ehmcke, J, Wistuba, J, Schlatt, S. Spermatogonial stem cells: questions, models and perspectives. Hum Reprod Update 2006;12(3):275282.Google Scholar
T’Sjoen, G, Van Caenegem, E, Wierckx, K. Transgenderism and reproduction. Curr Opin Endocrinol Diabetes Obes 2012;20:575579.Google Scholar
Schneider, F, Scheffer, B, Dabel, J, et al. Options for fertility treatments for trans women in Germany. J Clin Med 2019;8(5):730.Google Scholar
Jindarak, S, Nilprapha, K, Atikankul, T, et al. Spermatogenesis abnormalities following hormonal therapy in transwomen. BioMed Res Int 2018;2018:7919481.Google Scholar
Vereecke, G, Defreyne, J, Van Saen, D, et al. Characterisation of testicular function and spermatogenesis in transgender women. Hum Reprod 2021; 36(1):515.Google ScholarPubMed
Nieschlag, E, Vorona, E, Wenk, M, Hemker, AK, Kamischke, A, Zitzmann, M. Hormonal male contraception in men with normal and subnormal semen parameters. Int J Androl 2011;34(6):556567.Google Scholar
Meriggiola, MC, Costantino, A, Cerpolini, S, et al. Testosterone undecanoate maintains spermatogenic suppression induced by cyproterone acetate plus testosterone undecanoate in normal men. J Clin Endocrinol Metab 2003;88(12):58185826.Google Scholar
Hezavehei, M, Sharafi, M, Kouchesfahani, HM, et al. Sperm cryopreservation: a review on current molecular cryobiology and advanced approaches. RBMO 2018;37(3):327339.Google Scholar
Di Santo, M, Tarozzi, N, Nadalini, M, Borini, A. Human sperm cryopreservation: update on techniques, effect on DNA integrity, and implications for ART. Adv Urol 2011;2012:854837.Google ScholarPubMed
De Vries, A, Klink, D, Cohen-Kettenis, P. What the primary care pediatrician needs to know about gender incongruence and gender dysphoria in children and adolescents. Pediatr Clin N Am 2016;2016:0021-3955/16.Google Scholar
Deutsches IVF Register. Jahrbuch 2019. J Reprod Med Endocrinol 2020;5:199239.Google Scholar
De Sutter, P, Kira, K, Verschoor, A, Hotimsky, A. The desire to have children and the preservation of fertility in transsexual women: a survey. Int J Transgend 2002;2002: 221291631.Google Scholar
De Sutter, P. Gender reassignment and assisted reproduction: present and future reproductive options for transsexual people. Hum Reprod 2001;16:612614.CrossRefGoogle ScholarPubMed
Wierckx, K, Stuyver, I, Weyers, S, et al. Sperm freezing in transsexual women. Arch Sex Behav 2012;41:10691071.Google Scholar
Nixon, L. The right to (trans) parent: a reproductive justice approach to reproductive rights, fertility, and family-building issues facing transgender people. William & Mary Journal of Race, Gender, and Social Justice 2013;20:73103.Google Scholar
Ross, LJ. Reproductive justice as intersectional feminist activism. Souls 2017;19:286314.Google Scholar

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