Skip to main content Accessibility help

We use cookies to distinguish you from other users and to provide you with a better experience on our websites. Close this message to accept cookies or find out how to manage your cookie settings.

Close cookie message
×
Hostname: page-component-78c5997874-g7gxr Total loading time: 0 Render date: 2024-11-02T19:15:03.428Z Has data issue: false hasContentIssue false

Chapter 14 - Ingestions

Published online by Cambridge University Press:  01 June 2018

By
Stephen M. Blumberg ,
Vincent Nguyen  and
Katherine J. Chou
Edited by
Jeffrey C. Gershel  and
Ellen F. Crain
Jeffrey C. Gershel
Affiliation:
Albert Einstein College of Medicine, New York
Ellen F. Crain
Affiliation:
Albert Einstein College of Medicine, New York
Get access

Summary

A summary is not available for this content so a preview has been provided. Please use the Get access link above for information on how to access this content.
Image of the first page of this content. For PDF version, please use the ‘Save PDF’ preceeding this image.'
Type
Chapter
Information
Clinical Manual of Emergency Pediatrics , pp. 442 - 492
Publisher: Cambridge University Press
Print publication year: 2018

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Bibliography

Albertson, TE, Owen, KP, Sutter, ME, Chan, AL. Gastrointestinal decontamination in the acutely poisoned patient. Int J Emerg Med. 2011;12(4):65.CrossRefGoogle Scholar
Barrueto, F Jr., Gattu, R, Mazer-Amirshahi, M. Updates in the general approach to the pediatric poisoned patient. Pediatr Clin North Am. 2013;60(5):1203–1220.Google Scholar
Calello, DP, Henretig, FM. Pediatric toxicology: specialized approach to the poisoned child. Emerg Med Clin North Am. 2014;32(1):29–52.Google Scholar
Marraffa, JM, Cohen, V, Howland, MA. Antidotes for toxicological emergencies: a practical review. Am J Health Syst Pharm. 2012;69(3):199–212.CrossRefGoogle ScholarPubMed
Mowry, JB, Spyker, DA, Cantilena, LR Jr, McMillan, N, Ford, M. 2013 annual report of the American Association of Poison Control Centers’ National Poison Data System (NPDS): 31st annual report. Clin Toxicol (Phila). 2014;52(10):1032–1283.CrossRefGoogle Scholar

Bibliography

Blackford, MG, Felter, T, Gothard, MD, Reed, MD. Assessment of the clinical use of intravenous and oral N-acetylcysteine in the treatment of acute acetaminophen poisoning in children: a retrospective review. Clin Ther. 2011;33(9):1322–1330.Google Scholar
Lancaster, EM, Hiatt, JR, Zarrinpar, A. Acetaminophen hepatotoxicity: an updated review. Arch Toxicol. 2015;89(2):193–199.Google Scholar
Rumack, BH, Bateman, DN. Acetaminophen and acetylcysteine dose and duration: past, present and future. Clin Toxicol. 2012;50(2):91–98.CrossRefGoogle ScholarPubMed
Seifert, SA, Kirschner, RI, Martin, TG, et al. Acetaminophen concentrations prior to 4 hours of ingestion: impact on diagnostic decision-making and treatment. Clin Toxicol (Phila). 2015;53(7):618–623.CrossRefGoogle ScholarPubMed
Shastri, N. Intravenous acetaminophen use in pediatrics. Pediatr Emerg Care. 2015;31(6):444–448.CrossRefGoogle ScholarPubMed

Bibliography

Cooper, WO, Habel, LA, Sox, CM, et al. ADHD drugs and serious cardiovascular events in children and young adults. N Engl J Med. 2011;365:1896–1904.Google Scholar
Cortese, S, Holtmann, M, Banaschewski, T, et al. Practitioner review: current best practice in the management of adverse events during treatment with ADHD medications in children and adolescents. J Child Psychol Psychiatry. 2013;54(3):227–246.Google Scholar
Spiller, HA, Hays, HL, Aleguas, A. Overdose of drugs for attention-deficit hyperactivity disorder: clinical presentation, mechanisms of toxicity, and management. CNS Drugs. 2013;27:531–543.CrossRefGoogle ScholarPubMed

Bibliography

Dawson, AH, Buckley, NA. Pharmacological management of anticholinergic delirium: theory, evidence and practice. Br J Clin Pharmacol. 2016;81(3):516–524.Google Scholar
Glatstein, MM, Alabdulrazzaq, F, Garcia-Bournissen, F, Scolnik, D. Use of physostigmine for hallucinogenic plant poisoning in a teenager: case report and review of the literature. Am J Ther. 2012;19(5):384–388.Google Scholar
Glatstein, M, Alabdulrazzaq, F, Scolnik, D. Belladonna alkaloid intoxication: the 10-year experience of a large tertiary care pediatric hospital. Am J Ther. 2016;23(1):e74–e77.Google Scholar

Bibliography

Bruccoleri, RE, Burns, MM. A literature review of the use of sodium bicarbonate for the treatment of QRS widening. J Med Toxicol. 2016;12(1):121–129.CrossRefGoogle ScholarPubMed
Kant, S, Liebelt, E. Recognizing serotonin toxicity in the pediatric emergency department. Pediatr Emerg Care. 2012;28(8):817–821.CrossRefGoogle ScholarPubMed
Stork, CM. Serotonin reuptake inhibitors and atypical antidepressants. In Hoffman, RS, Howland, MA, Lewin, NA, Nelson, LS, Goldfrank, LR (eds.) Goldfrank’s Toxicologic Emergencies (10th edn.). New York: McGraw-Hill, 2015; 1018–1028.Google Scholar
Wang, RZ, Vashistha, V, Kaur, S, Houchens, NW. Serotonin syndrome: preventing, recognizing, and treating it. Cleve Clin J Med. 2016;83(11):810–817.Google Scholar

Bibliography

Meli, M, Rauber-Lüthy, C, Hoffmann-Walbeck, P, et al. Atypical antipsychotic poisoning in young children: a multicentre analysis of poisons centres data. Eur J Pediatr. 2014;173:743–750.CrossRefGoogle ScholarPubMed
Pileggi, DJ, Cook, AM. Neuroleptic malignant syndrome. Ann Pharmacother. 2016;50(11):973–981.Google Scholar
Rasimas, JJ, Liebelt, EL. Adverse effects and toxicity of the atypical antipsychotics: what is important for the pediatric emergency medicine practitioner. Clin Pediatr Emerg Med. 2012;13(4):300–310.CrossRefGoogle ScholarPubMed
Tse, L, Barr, AM, Scarapicchia, V, Vila-Rodriguez, F. Neuroleptic malignant syndrome: a review from a clinically oriented perspective. Curr Neuropharmacol. 2015;13(3):395–406.Google Scholar

Bibliography

Graudins, A, Lee, HM, Druda, D. Calcium channel antagonist and beta-blocker overdose: antidotes and adjunct therapies. Br J Clin Pharmacol. 2016;81(3):453–461.Google Scholar
Jang, DH, Spyres, MB, Fox, L, Manini, AF. Toxin-induced cardiovascular failure. Emerg Med Clin North Am. 2014;32(1):79–102.CrossRefGoogle ScholarPubMed
Palatnick, W, Jelic, T. Emergency department management of calcium-channel blocker, beta blocker, and digoxin toxicity. Emerg Med Pract. 2014;16(2):1–19.Google ScholarPubMed
Truitt, CA, Brooks, DE, Dommer, P, LoVecchio, F. Outcomes of unintentional beta-blocker or calcium channel blocker overdoses: a retrospective review of poison center data. J Med Toxicol. 2012;8(2):135–139.Google Scholar

Bibliography

Beauchamp, GA, Johnson, AR, Crouch, BI, et al. A retrospective study of clinical effects of powdered caffeine exposures reported to three US poison control centers. J Med Toxicol. 2016;12(3):295–300.CrossRefGoogle ScholarPubMed
Jabbar, SB, Hanly, MG. Fatal caffeine overdose: a case report and review of literature. Am J Forensic Med Pathol. 2013;34(4):321–324.CrossRefGoogle ScholarPubMed
Seifert, SM, Schaechter, JL, Hershorin, ER, Lipshultz, SE. Health effects of energy drinks on children, adolescents, and young adults. Pediatrics. 2011;127(3):511–528.CrossRefGoogle ScholarPubMed

Bibliography

Graudins, A, Lee, HM, Druda, D. Calcium channel antagonist and beta-blocker overdose: antidotes and adjunct therapies. Br J Clin Pharmacol. 2016;81(3):453–461.Google Scholar
Palatnick, W, Jelic, T. Emergency department management of calcium-channel blocker, beta blocker, and digoxin toxicity. Emerg Med Pract. 2014;16(2):1–19.Google ScholarPubMed
Shenoy, S, Lankala, S, Adigopula, S. Management of calcium channel blocker overdoses. J Hosp Med. 2014;9(10):663–668.Google Scholar
St-Onge, M, Dubé, PA, Gosselin, S, et al. Treatment for calcium channel blocker poisoning: a systematic review. Clin Toxicol (Phila). 2014; 52:926–944.Google Scholar

Bibliography

Bleecker, ML. Carbon monoxide intoxication. Handb Clin Neurol. 2015;131:191–203.Google Scholar
Cho, CH, Chiu, NC, Ho, CS, Peng, CC. Carbon monoxide poisoning in children. Pediatr Neonatol. 2008;49:121–125.Google Scholar
Macnow, TE, Waltzman, ML. Carbon monoxide poisoning in children: diagnosis and management in the emergency department. Pediatr Emerg Med Pract. 2016;13(9):1–24.Google Scholar
Tomaszewski, C: Carbon monoxide. In Hoffman, RS, Howland, MA, Lewin, NA, Nelson, LS, Goldfrank, LR (eds.) Goldfrank’s Toxicologic Emergencies (10th edn.). New York: McGraw-Hill Education, 2015; 1581–1593.Google Scholar
Weaver, LK. Carbon monoxide poisoning. N Engl J Med. 2009;360:1217–1225.Google Scholar

Bibliography

Arevalo-Silva, C, Eliashar, R, Wohlgelernter, J, Elidan, J, Gross, M. Ingestion of caustic substances: a 15 year experience. Laryngoscope. 2006;116:1422–1426.Google Scholar
Shub, MD. Therapy of caustic ingestion: new treatment considerations. Curr Opin Pediatr. 2015;27(5):609–613.CrossRefGoogle ScholarPubMed
Uygun, I. Caustic oesophagitis in children: prevalence, the corrosive agents involved, and management from primary care through to surgery. Curr Opin Otolaryngol Head Neck Surg. 2015;23(6):423–432.Google Scholar
Valdez, AL, Casavant, MJ, Spiller, HA, et al. Pediatric exposure to laundry detergent pods. Pediatrics. 2014;134:1127–1135.Google Scholar
Wightman, RS, Read, KB, Hoffman, RS. Evidence-based management of caustic exposures in the emergency department. Emerg Med Pract. 2016;18(5):1–17.Google ScholarPubMed

Bibliography

Eddleston, M, Chowdhury, FR. Pharmacological treatment of organophosphorus insecticide poisoning: the old and the (possible) new. Br J Clin Pharmacol. 2016;81(3):462–470.Google Scholar
Eddleston, M, Clark, RF. Insecticides: organic phosphorus compounds and carbamates. In Hoffman, RS, Howland, MA, Lewin, NA, Nelson, LS, Goldfrank, LR (eds.) Goldfrank’s Toxicologic Emergencies (10th edn.). New York: McGraw-Hill, 2015; 1409–1424.Google Scholar
King, AM, Aaron, CK. Organophosphate and carbamate poisoning. Emerg Med Clin North Am. 2015;33(1):133–151.Google Scholar
Vale, A, Lotti, M. Organophosphorus and carbamate insecticide poisoning. Handb Clin Neurol. 2015;131:149–168.Google Scholar

Bibliography

Ahmad, SA, Scolnik, D, Snehal, V, Glatstein, M. Use of naloxone for clonidine intoxication in the pediatric age group: case report and review of the literature. Am J Ther. 2015;22(1):e14–e16.Google Scholar
Spiller, HA, Hays, HL, Aleguas, A Jr. Overdose of drugs for attention-deficit hyperactivity disorder: clinical presentation, mechanisms of toxicity, and management. CNS Drugs. 2013;27(7):531–543.CrossRefGoogle ScholarPubMed
Wang, GS, Le Lait, MC, Heard, K. Unintentional pediatric exposures to central alpha-2 agonists reported to the National Poison Data System. J Pediatr. 2014;164(1):149–152.Google Scholar

Bibliography

Isbister, GK, Prior, F, Kilham, HA. Restricting cough and cold medicines in children. J Paediatr Child Health. 2012;48(2):91–98.Google Scholar
Paul, IM, Reynolds, KM, Kauffman, RE, et al. Adverse events associated with pediatric exposures to dextromethorphan. Clin Toxicol (Phila). 2017;55(1):25–32.Google Scholar

Bibliography

Chan, BS, Buckley, NA. Digoxin-specific antibody fragments in the treatment of digoxin toxicity. Clin Toxicol (Phila). 2014;52(8):824–836.Google Scholar
Moffett, BS, Garner, A, Zapata, T, et al. Serum digoxin concentrations and clinical signs and symptoms of digoxin toxicity in the paediatric population. Cardiol Young. 2016;26(3):493–498.CrossRefGoogle ScholarPubMed
Palatnick, W, Jelic, T. Emergency department management of calcium-channel blocker, beta blocker, and digoxin toxicity. Emerg Med Pract. 2014;16(2):1–19.Google Scholar
Pincus, M. Management of digoxin toxicity. Aust Prescr. 2016;39(1):18–20.Google Scholar

Bibliography

Huestis, MA, Tyndale, RF. Designer drugs 2.0. Clin Pharmacol Ther. 2017;101(2):152–157.Google Scholar
Nelson, ME, Bryant, SM, Aks, SE. Emerging drugs of abuse. Emerg Med Clin North Am. 2014;32:1–28.CrossRefGoogle ScholarPubMed
Richards, JR, Garber, D, Laurin, EG, et al. Treatment of cocaine cardiovascular toxicity: a systematic review. Clin Toxicol (Phila). 2016;54(5):345–364.Google Scholar
Tenenbein, M. Do you really need that emergency drug screen? Clin Toxicol (Phila). 2009;47:286–291.Google Scholar

Bibliography

Minera, G, Robinson, E. Accidental acute alcohol intoxication in infants: review and case report. J Emerg Med. 2014;47(5):524–526.Google Scholar
Rayar, P, Ratnapalan, S. Pediatric ingestions of house hold products containing ethanol: a review. Clin Pediatr (Phila). 2013;52:203–209.CrossRefGoogle ScholarPubMed
Yip, L. Ethanol. In Hoffman, RS, Howland, MA, Lewin, NA, Nelson, LS, Goldfrank, LR (eds.) Goldfrank’s Toxicologic Emergencies (10th edn.). New York: McGraw-Hill, 2015; 1082–1093.Google Scholar

Bibliography

Hussain, SZ, Bousvaros, A, Gilger, M, et al. Management of ingested magnets in children. J Pediatr Gastroenterol Nutr. 2012;55(3):239–242.Google Scholar
Jayachandra, S, Eslick, GD. A systematic review of paediatric foreign body ingestion: presentation, complications, and management. Int J Pediatr Otorhinolaryngol. 2013;77(3):311–317.CrossRefGoogle ScholarPubMed
Kramer, RE, Lerner, DG, Lin, T, Manfredi, M, et al. Management of ingested foreign bodies in children: a clinical report of the NASPGHAN Endoscopy Committee. J Pediatr Gastroenterol Nutr. 2015;60(4):562–574.CrossRefGoogle ScholarPubMed
Litovitz, T, Whitaker, N, Clark, L, White, NC, Marsolek, M. Emerging battery ingestion hazard: clinical implications. Pediatrics. 2010;125(6):1168–1177.Google Scholar
Wright, CC, Closson, FT. Updates in pediatric gastrointestinal foreign bodies. Pediatr Clin North Am. 2013;60(5):1221–1239.CrossRefGoogle ScholarPubMed

Bibliography

Beuhler, MC, Gala, PK, Wolfe, HA, Meaney, PA, Henretig, FM. Laundry detergent “pod” ingestions: a case series and discussion of recent literature. Pediatr Emerg Care. 2013;29(6):743–747CrossRefGoogle ScholarPubMed
Makrygianni, EA, Palamidou, F, Kaditis, AG. Respiratory complications following hydrocarbon aspiration in children. Pediatr Pulmonol. 2016;51(6):560–569.Google Scholar
Niaz, K, Bahadar, H, Maqbool, F, Abdollahi, M. A review of environmental and occupational exposure to xylene and its health concerns. EXCLI J. 2015;14:1167–1186.Google Scholar
Tormoehlen, LM, Tekulve, KJ, Nañagas, KA. Hydrocarbon toxicity: a review. Clin Toxicol (Phila). 2014;52(5):479–489.Google Scholar

Bibliography

Chang, TP, Rangan, C. Iron poisoning: a literature-based review of epidemiology, diagnosis, and management. Pediatr Emerg Care. 2011;27(10):978–985.CrossRefGoogle ScholarPubMed
Gumber, MR, Kute, VB, Shah, PR, et al. Successful treatment of severe iron intoxication with gastrointestinal decontamination, deferoxamine, and hemodialysis. Ren Fail. 2013;35(5):729–731.Google Scholar
Madiwale, T, Liebelt, E. Iron: not a benign therapeutic drug. Curr Opin Pediatr. 2006;18:174–179.Google Scholar
Thanacoody, R, Caravati, EM, Troutman, B, et al. Position paper update: whole bowel irrigation for gastrointestinal decontamination of overdose patients. Clin Toxicol (Phila). 2015;53:5–12.Google Scholar

Bibliography

Chauhan, V, Sharma, R, Sharma, K, et al. Naphthalene poisoning manifesting as hemoglobinuria. Toxicol Int. 2014;21(3):314–315.Google Scholar
Kovacic, P, Somanathan, R. Nitroaromatic compounds: environmental toxicity, carcinogenicity, mutagenicity, therapy and mechanism. J Appl Toxicol. 2014;34(8):810–824.Google Scholar
MacKinney, TG, Soti, KR, Shrestha, P, Basnyat, B. Camphor: an herbal medicine causing grand mal seizures. BMJ Case Rep. 2015 11;2015.Google Scholar
Sudakin, DL, Stone, DL, Power, L. Naphthalene mothballs: emerging and recurring issues and their relevance to environmental health. Curr Top Toxicol. 2011;7:13–19.Google Scholar

Bibliography

Argentieri, J, Morrone, K, Pollack, Y. Acetaminophen and ibuprofen overdosage. Pediatr Rev. 2012;33(4):188–189.Google Scholar
Hunter, LJ, Wood, DM, Dargan, PI. The patterns of toxicity and management of acute nonsteroidal anti-inflammatory drug (NSAID) overdose. Open Access Emerg Med. 2011;3:39–48.Google Scholar
Lodise, M, De-Giorgio, F, Rossi, R, d’Aloja, E, Fucci, N. Acute ibuprofen intoxication: report on a case and review of the literature. Am J Forensic Med Pathol. 2012;33(3):242–246.Google Scholar
Unzueta, A, Vargas, HE. Nonsteroidal anti-inflammatory drug-induced hepatoxicity. Clin Liver Dis. 2013;17(4):643–656Google Scholar

Bibliography

Dougherty, PP, Lee, SC, Lung, D, Klein-Schwartz, W. Evaluation of the use and safety of octreotide as antidotal therapy for sulfonylurea overdose in children. Pediatr Emerg Care. 2013;29(3):292–295.Google Scholar
Glatstein, M, Scolnik, D, Bentur, Y. Octreotide for the treatment of sulfonylurea poisoning. Clin Toxicol (Phila). 2012;50:795–804.Google Scholar
Klein-Schwartz, W, Stassinos, GL, Isbister, GK. Treatment of sulfonylurea and insulin overdose. Br J Clin Pharmacol. 2016;81(3):496–504.CrossRefGoogle ScholarPubMed
Lung, DD, Olson, KR. Hypoglycemia in pediatric sulfonylurea poisoning: an 8-year poison center retrospective study. Pediatrics. 2011;127:e1558–e1564.Google Scholar

Bibliography

Card, DJ, Francis, S, Deuchande, K, Harrington, DJ. Superwarfarin poisoning and its management. BMJ Case Rep. 2014;2014. DOI: 10.1136/bcr-2014-206360.Google Scholar
Fang, Y, Ye, D, Tu, C, et al. Superwarfarin rodent poisons and hemorrhagic disease. Epidemiology. 2012;23(6):932–934.Google Scholar
King, N, Tran, MH. Long-acting anticoagulant rodenticide (superwarfarin) poisoning: a review of its historical development, epidemiology, and clinical management. Transfus Med Rev. 2015;29(4):250–258Google Scholar
Schulman, S, Furie, B. How I treat poisoning with vitamin K antagonists. Blood. 2015;125(3):438–442.Google Scholar

Bibliography

Calello, DP, Henretig, FM. Pediatric toxicology: specialized approach to the poisoned child. Emerg Med Clin North Am. 2014;32(1):29–52.Google Scholar
Flomenbaum, NE. Salicylates. In Hoffman, RS, Howland, MA, Lewin, NA, Nelson, LS, Goldfrank, LR (eds.) Goldfrank’s Toxicologic Emergencies (10th edn.). New York: McGraw-Hill, 2015; 516–527.Google Scholar
Juurlink, DN, Gosselin, S, Kielstein, JT, et al. Extracorporeal treatment for salicylate poisoning: systematic review and recommendations from the EXTRIP workgroup. Ann Emerg Med. 2015;66(2):165–181.Google Scholar
Robinson, K, Rauch, A, Hannan, L. Salicylate poisoning following topical administration of methylsalicylate. Emerg Med Australas. 2015;27(4):374–375.Google Scholar
Shively, RM, Hoffman, RS, Manini, AF. Acute salicylate poisoning: risk factors for severe outcome. Clin Toxicol (Phila). 2017;55(3):175–180.CrossRefGoogle ScholarPubMed

Bibliography

Jammalamadaka, D, Raissi, S. Ethylene glycol, methanol, and isopropyl alcohol intoxication. Am J Med Sci. 2010;339:276–281.Google Scholar
Kraut, JA. Diagnosis of toxic alcohols: limitations of present methods. Clin Toxicol (Phila). 2015;53(7):589–595.Google Scholar
Kruse, JA. Methanol and ethylene glycol intoxication. Crit Care Clin. 2012;28(4):661–711.Google Scholar
McMartin, K, Jacobsen, D, Hovda, KE. Antidotes for poisoning by alcohols that form toxic metabolites. Br J Clin Pharmacol. 2016;81(3):505–515.Google Scholar

Bibliography

Body, R, Bartram, T, Azam, F, Mackway-Jones, K. Guidelines in Emergency Medicine Network (GEMNet): guideline for the management of tricyclic antidepressant overdose. Emerg Med J. 2011;28(4):347–368.Google Scholar
Bruccoleri, RE, Burns, MM. A literature review of the use of sodium bicarbonate for the treatment of QRS widening. J Med Toxicol. 2016;12(1):121–129.Google Scholar
Carvalho, AF, Sharma, MS, Brunoni, AR, Vieta, E, Fava, GA. The safety, tolerability and risks associated with the use of newer generation antidepressant drugs: a critical review of the literature. Psychother Psychosom. 2016;85(5):270–288.Google Scholar
O’Sullivan, JC, Johnson, AD, Waterman, MA. Comparative resuscitation measures for the treatment of desipramine overdose. Mil Med. 2014;179(11):1266–1272.CrossRefGoogle ScholarPubMed

Save book to Kindle

To save this book to your Kindle, first ensure [email protected] is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Available formats
×

Save book to Dropbox

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

Available formats
×