Skip to main content Accessibility help

We use cookies to distinguish you from other users and to provide you with a better experience on our websites. Close this message to accept cookies or find out how to manage your cookie settings.

Close cookie message
×
Hostname: page-component-586b7cd67f-vdxz6 Total loading time: 0 Render date: 2024-11-28T07:33:40.407Z Has data issue: false hasContentIssue false

Chapter 18 - Pharmacological and nonpharmacological treatment of chemotherapy-induced nausea and vomiting

from Section 3 - Management of maternal complications during treatment

Published online by Cambridge University Press:  05 December 2011

By
Caroline Maltepe
Edited by
Gideon Koren  and
Michael Lishner
Gideon Koren
Affiliation:
University of Toronto
Michael Lishner
Affiliation:
Tel-Aviv University
Get access

Summary

The most common cause of nausea and vomiting (NV) in patients with cancer is chemotherapy. There are several pharmacological and nonpharmacological treatments available to treat NV, and many studies show their safety in human pregnancy. NV is usually multifactorial in etiology, resulting from the disease process itself, drug therapy, and/or radiotherapy, chemotherapy, or surgery. A variety of antiemetics have been used for the treatment of various causes of NV associated with cancer and its treatment. Metoclopramide is a dopamine receptor antagonist, and high doses are given for chemotherapy-induced nausea and vomiting (CINV). Corticosteroids that have been commonly used for CINV are dexamethasone and prednisone. Phenothiazines, such as prochlorperazine, promethazine, and chlorpromazine, are commonly used for low emetic risk and breakthrough CINV. Nonpharmacological treatments that are commonly used to treat nausea and vomiting in pregnancy have also shown to be beneficial when given in addition to the antiemetic regimen of CINV.

Keywords

B-cell lymphomasBurkitt's lymphomachemotherapynon-Hodgkin's lymphomapregnancymantle cell lymphomachronic lymphocytic leukemiafollicular lymphoma
Type
Chapter
Information
Cancer in Pregnancy and Lactation
The Motherisk Guide
 , pp. 134 - 142
Publisher: Cambridge University Press
Print publication year: 2011

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

Save book to Kindle

To save this book to your Kindle, first ensure [email protected] is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Available formats
×

Save book to Dropbox

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

Available formats
×