This chapter describes the continued, still ongoing, trajectory of the Planetary Boundaries (PB) framework and how it has co-evolved with the “Anthropocene,” another concept with Stockholm roots. During the course of the second decade of the new century, ethical aspects were increasingly taken on board. Will Steffen, former Director of the Stockholm-based International Geosphere Biosphere Program (IGBP), was the lead author of a second PB article in Science in 2015. Like the first Nature article in 2009, a sizable share of the co-authors had institutional involvement or other affiliation with Stockholm. This new iteration developed the ethical challenges of sharing the “safe operating space” inside boundaries among regions, nations, and societal groups. Steffen was also a member of the Anthropocene Working Group appointed by the Stratigraphic Committee to make the case for Anthropocene as a new geological era. The chapter articulates the significance of the overlap between the PB and Anthropocene processes and debates. These drew considerable interest from scholars in the social sciences and humanities, which helped make both issues concerns of epistemology and Weltanschauung.