Hostname: page-component-cd9895bd7-gbm5v Total loading time: 0 Render date: 2024-12-28T14:11:10.139Z Has data issue: false hasContentIssue false

Grading the thalamus: how can an ‘Eph’ be excellent?

Published online by Cambridge University Press:  13 March 2007

Colenso M. Speer
Affiliation:
Center for Neuroscience, University of California, Davis, USA
Barbara Chapman
Affiliation:
Center for Neuroscience, University of California, Davis, USA

Abstract

The Eph family of receptor tyrosine kinases and their partner ligands, the ephrins, mediate cell–cell interactions in the developing nervous system. Signaling events between Eph receptors and ephrin ligands on interacting cells affect the growth, maturation, migration and connectivity of individual neurons and neural networks. Here we review the known roles of Eph–ephrin signaling in the development of the thalamus and its connections, and pose new questions for experimental study.

Type
Review Article
Copyright
2007 Cambridge University Press

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)