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Semantic knowledge for famous names in mild cognitive impairment

Published online by Cambridge University Press:  01 January 2009

MICHAEL SEIDENBERG ,
LESLIE GUIDOTTI ,
KRISTY A. NIELSON ,
JOHN L. WOODARD ,
SALLY DURGERIAN ,
Qi ZHANG ,
AMELIA GANDER ,
PIERO ANTUONO  and
STEPHEN M. RAO
MICHAEL SEIDENBERG*
Affiliation:
Department of Psychology, Rosalind Franklin University of Medicine and Science, North Chicago, Illinois
LESLIE GUIDOTTI
Affiliation:
Department of Psychology, Rosalind Franklin University of Medicine and Science, North Chicago, Illinois
KRISTY A. NIELSON
Affiliation:
Department of Psychology and the Integrative Neuroscience Research Center, Marquette University, Milwaukee, Wisconsin Department of Neurology, Medical College of Wisconsin, Milwaukee, Wisconsin
JOHN L. WOODARD
Affiliation:
Department of Psychology, Wayne State University, Detroit, Michigan
SALLY DURGERIAN
Affiliation:
Functional Imaging Research Center, Medical College of Wisconsin, Milwaukee, Wisconsin Department of Neurology, Medical College of Wisconsin, Milwaukee, Wisconsin
Qi ZHANG
Affiliation:
Functional Imaging Research Center, Medical College of Wisconsin, Milwaukee, Wisconsin Department of Neurology, Medical College of Wisconsin, Milwaukee, Wisconsin
AMELIA GANDER
Affiliation:
Functional Imaging Research Center, Medical College of Wisconsin, Milwaukee, Wisconsin Department of Neurology, Medical College of Wisconsin, Milwaukee, Wisconsin
PIERO ANTUONO
Affiliation:
Foley Center for Aging and Development, Medical College of Wisconsin, Milwaukee, Wisconsin Functional Imaging Research Center, Medical College of Wisconsin, Milwaukee, Wisconsin Department of Neurology, Medical College of Wisconsin, Milwaukee, Wisconsin
STEPHEN M. RAO
Affiliation:
Schey Center for Cognitive Neuroimaging, Cleveland Clinic, Cleveland, Ohio
*
*Correspondence and reprint requests to: Michael Seidenberg, 3333 Green Bay Road, North Chicago, IL 60064. E-mail: [email protected]
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Abstract

Person identification represents a unique category of semantic knowledge that is commonly impaired in Alzheimer’s disease (AD), but has received relatively little investigation in patients with mild cognitive impairment (MCI). The current study examined the retrieval of semantic knowledge for famous names from three time epochs (recent, remote, and enduring) in two participant groups: 23 amnestic MCI (aMCI) patients and 23 healthy elderly controls. The aMCI group was less accurate and produced less semantic knowledge than controls for famous names. Names from the enduring period were recognized faster than both recent and remote names in both groups, and remote names were recognized more quickly than recent names. Episodic memory performance was correlated with greater semantic knowledge particularly for recent names. We suggest that the anterograde memory deficits in the aMCI group interferes with learning of recent famous names and as a result produces difficulties with updating and integrating new semantic information with previously stored information. The implications of these findings for characterizing semantic memory deficits in MCI are discussed. (JINS, 2009, 15, 9–18.)

Keywords

Semantic memoryAgingFame recognitionPerson identityRemote memoryTemporal gradient
Type
Research Articles
Information
Journal of the International Neuropsychological Society , Volume 15 , Issue 1 , January 2009 , pp. 9 - 18
Copyright
Copyright © INS 2009

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References

REFERENCES

Adlam, A., Bozeat, S., Arnold, R., Watson, P., & Hodges, J. (2006). Semantic knowledge in mild cognitive impairment and mild Alzheimer’s disease. Cortex, 42, 675–684.CrossRefGoogle ScholarPubMed
Albert, M., Butters, N., & Brandt, J. (1981). Development of remote memory loss patients with Huntington’s disease. Journal of Clinical Neuropsychology, 3, 1–12.CrossRefGoogle ScholarPubMed
Albert, M., Butters, N., & Levin, J. (1979). Temporal gradients in the retrograde amnesia of patients with Korsakoff’s disease. Archives of Neurology, 36, 211–216.CrossRefGoogle ScholarPubMed
Albert, M., Moss, M., Tanzi, R., & Jones, K. (2001). Preclinical prediction of AD using neuropsychological tests. Journal of the International Neuropsychological Society; JINS, 7, 631–639.CrossRefGoogle ScholarPubMed
Alladi, S., Arnold, R., Mitchell, J., Nestor, P., & Hodges, J. (2006). Mild cognitive impairment: Applicability of research criteria in a memory clinic and characterization of cognitive profile. Psychological Medicine, 36, 507–515.CrossRefGoogle Scholar
Backman, L. & Herlitz, A. (1990). The relationship between prior knowledge and face recognition in normal aging and Alzheimer’s disease. Journal of Gerontology, 45, 94–100.CrossRefGoogle ScholarPubMed
Barr, W., Goldberg, E., Wasserstein, J., & Novelly, R. (1990). Retrograde amnesia following unilateral temporal lobectomy. Neuropsychologia, 28, 243–255.CrossRefGoogle ScholarPubMed
Beatty, W., Salmon, D., Butters, N., Heindel, W., & Granholm, E. (1988). Retrograde amnesia in patients with Alzheimer’s disease or Huntington’s disease. Neurobiology of Aging, 9, 181–186.CrossRefGoogle ScholarPubMed
Becker, J., Lopez, O., & Boller, F. (1995). Understanding impaired analysis of faces by patients with probable Alzheimer’s disease. Cortex, 31, 129–137.CrossRefGoogle ScholarPubMed
Bizzozero, I., Capitani, E., Paglioni, P., Luchelli, F., Saetti, M., & Spinnler, H. (2008). Recollection of public events in healthy people: A latent variable stochastic approach to disentangling retrieval and encoding. Cortex, 44, 150–160.CrossRefGoogle Scholar
Chan, A., Salmon, D., Butters, N., & Johnson, S. (1995). Semantic network abnormality predicts rate of cognitive decline in patients with probable Alzheimer’s disease. Journal of the International Neuropsychological Society; JINS, 1, 297–303.CrossRefGoogle ScholarPubMed
Crutch, S. & Warrington, E. (2004). The semantic organisation of proper nouns: The case of people and brand names. Neuropsychologia, 42, 584–596.CrossRefGoogle ScholarPubMed
Delazer, M., Semenza, C., Reiner, M., Hofer, R., & Benke, T. (2003). Anomia for people names in DAT – evidence for semantic and post-semantic impairments. Neuropsychologia, 41, 1593–1598.CrossRefGoogle ScholarPubMed
Denkova, E., Botzung, A., & Manning, L. (2006). Neural correlates of remembering/knowing famous people: An event-related fMRI study. Neuropsychologia, 44, 2783–2791.CrossRefGoogle ScholarPubMed
Douville, K., Woodard, J., Seidenberg, M., Leveroni, C., Nielson, K., Franczak, M., Antuono, P., & Rao, S. (2005). Medial temporal lobe activity for recognition of recent and remote famous names: An event-related fMRI study. Neuropsychologia, 43, 693–703.CrossRefGoogle ScholarPubMed
Dudas, R., Clague, F., Thompson, S., Graham, K., & Hodges, J. (2005). Episodic and semantic memory in mild cognitive impairment. Neuropsychologia, 43, 1266–1276.CrossRefGoogle ScholarPubMed
Estevez-Gonzalez, A., Garcia-Sanchez, C., Boltes, A., Otermin, P., Pascual-Sedano, B., Gironell, A., & Kulisevsky, J. (2004). Semantic knowledge of famous people in mild cognitive impairment and progression to Alzheimer’s disease. Dementia and Geriatric Cognitive Disorders, 17, 188–195.CrossRefGoogle ScholarPubMed
Folstein, M., Folstein, S., & McHugh, P. (1975). “Mini-mental state”. A practical method for grading the cognitive status of patients for the clinician. Journal of Psychiatric Research, 12, 189–198.CrossRefGoogle Scholar
Frutos-Alegria, M., Molto-Jorda, J., Morera-Guitart, J., Sanchez-Perez, A., & Ferrer-Navajas, M. (2007). The neuropsychological profile of mild cognitive impairment with involvement of multiple cognitive areas. The importance of amnesia in distinguishing two subtypes of patients. Revista de Neurologica, 44, 455–459.Google ScholarPubMed
Giffard, B., Desgranges, B., Nore-Mary, F., Lalevee, C., de la Sayette, V., Pasquier, F., & Eustache, F. (2001). The nature of semantic memory deficits in Alzheimer’s disease: New insights from hyperpriming effects. Brain, 124, 1522–1532.CrossRefGoogle ScholarPubMed
Greene, J. & Hodges, J. (1996). Identification of famous faces and famous names in early Alzheimer’s disease. Relationship to anterograde episodic and general semantic memory. Brain, 119, 111–128.CrossRefGoogle ScholarPubMed
Haist, F., Bowden, G., & Mao, H. (2001). Consolidation of human memory over decades revealed by functional magnetic resonance imaging. Nature Neuroscience, 4, 1139–1145.CrossRefGoogle ScholarPubMed
Hodges, J., Erzinclioglu, S., & Patterson, K. (2006). Evolution of cognitive deficits and conversion to dementia in patients with mild cognitive impairment: A very-long-term follow-up study. Dementia and Geriatric Cognitive Disorders, 21, 380–391.CrossRefGoogle ScholarPubMed
Hodges, J. & Graham, K. (1998). A reversal of the temporal gradient for famous person knowledge in semantic dementia: Implications for the neural organization of long-term memory. Neuropsychologia, 36, 803–825.CrossRefGoogle ScholarPubMed
Hodges, J. & Patterson, K. (1995). Is semantic memory consistently impaired early in the course of Alzheimer’s disease? Neuroanatomical and diagnostic implications. Neuropsychologia, 33, 441–459.CrossRefGoogle ScholarPubMed
Hodges, J., Salmon, D., & Butters, N. (1993). Recognition and naming of famous faces in Alzheimer’s disease: A cognitive analysis. Neuropsychologia, 31, 775–788.CrossRefGoogle ScholarPubMed
Jacobs, D., Sano, M., Dooneief, G., Marder, K., Bell, K., & Stern, Y. (2001). Neuropsychological detection and characterization of preclinical Alzheimer’s disease. Neurology, 45, 957–962.CrossRefGoogle Scholar
Joubert, S., Felician, O., Barbeau, E.J., Didic, M., Poncet, M., & Ceccaldi, M. (2008). Patterns of semantic memory impairment in mild cognitive impairment. Behavioural Neurology, 19, 35–40.CrossRefGoogle ScholarPubMed
Jurica, P., Leitten, C., & Mattis, S. (2001). Dementia Rating Scale-2 (DRS-2). Odessa, FL: Psychological Assessment Resources.Google Scholar
Kramer, J., Nelson, A., Johnson, J., Yaffe, K., Glenn, S., Rosen, H., & Miller, B. (2006). Multiple cognitive deficits in amnestic mild cognitive impairment. Dementia and Geriatric Cognitive Disorders, 22, 306–311.CrossRefGoogle ScholarPubMed
Lawton, M. and Brody, M. (1969). Assessment of older people: Self-maintaining and instrumental activities of daily living. Gerontologist, 9, 179–186.CrossRefGoogle ScholarPubMed
Loewenstein, D., Acevedo, A., Luis, C., Crum, T., Barker, W., & Duara, R. (2004). Semantic interference deficits and the detection of mild Alzheimer’s disease and mild cognitive impairment without dementia. Journal of the International Neuropsychological Society; JINS, 10, 91–100.CrossRefGoogle ScholarPubMed
Lopez, O., Becker, J., Jagust, W., Fitzpatrick, A., Carlson, M., DeKosky, S., Breitner, J., Lyketsos, C., Jones, B., Kawas, C., & Kuller, L. (2006). Neuropsychological characteristics of mild cognitive impairment subgroups. Journal of Neurology, Neurosurgery, and Psychiatry, 77, 159–165.CrossRefGoogle ScholarPubMed
Martin, A. & Fedio, P. (1983). Word production and comprehension in Alzheimer’s disease: The breakdown of semantic knowledge. Brain and Language, 19, 124–141.CrossRefGoogle ScholarPubMed
Mattis, S. (1988). Dementia Rating Scale (DRS). Odessa, FL: Psychological Assessment Resources.Google Scholar
McCarthy, R. & Warrington, E. (1990). Cognitive Neuropsychology: A Clinical Introduction. San Diego: Academic Press.Google Scholar
Moran, M., Seidenberg, M., Sabsevitz, D., Swanson, S., & Hermann, B. (2005). The acquisition of face and person identity information following anterior temporal lobectomy. Journal of the International Neuropsychological Society; JINS, 11, 237–248.CrossRefGoogle ScholarPubMed
Moscovitch, M. & Nadel, L. (1998). Consolidation and the hippocampal complex revisited: In defense of the multiple-trace model. Current Opinion in Neurobiology, 8, 297–300.CrossRefGoogle ScholarPubMed
Murphy, K., Rich, J., & Troyer, A. (2006). Verbal fluency patterns in amnestic mild cognitive impairment are characteristic of Alzheimer’s type dementia. Journal of the International Neuropsychological Society; JINS, 12, 570–574.CrossRefGoogle ScholarPubMed
Nadel, L. & Moscovitch, M. (1997). Memory consolidation, retrograde amnesia, and the hippocampal complex. Current Opinion in Neurobiology, 7, 217–227.CrossRefGoogle ScholarPubMed
Nielson, K., Douville, K., Seidenberg, M., Woodard, J., Miller, S., Franczak, M., Antuono, P., & Rao, S. (2006). Age-related functional recruitment for famous name recognition: An event-related fMRI study. Neurobiology of Aging, 27, 1494–1504.CrossRefGoogle ScholarPubMed
Nordlund, A., Rolstad, S., Hellstrom, P., Sjogren, M., Hansen, S., & Wallin, A. (2005). The Goteborg MCI study: Mild cognitive impairment is a heterogeneous condition. Journal of Neurology, Neurosurgery, and Psychiatry, 76, 1485–1490.CrossRefGoogle ScholarPubMed
Petersen, R. (2004). Mild cognitive impairment as a diagnostic entity. Journal of Internal Medicine, 256, 183–194.CrossRefGoogle ScholarPubMed
Petersen, R., Doody, R., Kurz, A., Mohs, R., Morris, J., Rabins, P., Ritchie, K., Rossor, M., Thal, L., & Winblad, B. (2001). Current concepts in mild cognitive impairment. Archives of Neurology, 58, 1985–1992.CrossRefGoogle ScholarPubMed
Piolino, P., Lamidey, V., Desgranges, B., & Eustache, F. (2007). The semantic and episodic subcomponents of famous person knowledge: Dissociation in healthy subjects. Neuropsychology, 21, 122–135.CrossRefGoogle ScholarPubMed
Rey, A. (1958). L’Examen clinique en psycholgie. Paris: Presse Universitaire de France.Google Scholar
Ribeiro, F., DeMendonca, A., & Guerrerio, M. (2006). Mild cognitive impairment: Deficits in cognitive domains other than memory. Dementia and Geriatric Cognitive Disorders, 21, 284–290.CrossRefGoogle ScholarPubMed
Ribeiro, F., Guerreiro, M., & DeMendonca, A. (2007). Verbal learning and memory deficits in Mild Cognitive Impairment. Journal of Clinical and Experimental Neuropsychology, 29, 187–197.CrossRefGoogle ScholarPubMed
Sadek, J., Johnson, S., White, D., Salmon, D., Taylor, K., Delapena, J., Paulsen, J., Heaton, R., & Grant, I. (2004). Retrograde amnesia in dementia: Comparison of HIV-associated dementia, Alzheimer’s disease, and Huntington’s disease. Neuropsychology, 18, 692–699.CrossRefGoogle ScholarPubMed
Seidenberg, M., Griffith, R., Sabsevitz, D., Moran, M., Haltiner, A., Bell, B., Swanson, S., Hammeke, T., & Hermann, B. (2002). Recognition and identification of famous faces in patients with unilateral temporal lobe epilepsy. Neuropsychologia, 40, 446–456.CrossRefGoogle ScholarPubMed
Semenza, C., Borgo, F., Mondini, S., Pasini, M., & Sgaramella, T. (2000). Proper names in the early stages of Alzheimer’s Disease. Brain and Cognition, 43, 384–387.Google ScholarPubMed
Small, J.A. & Sandhu, N. (2008). Episodic and semantic memory influences on picture naming in Alzheimer’s disease. Brain and Language, 104, 1–9.CrossRefGoogle ScholarPubMed
Squire, L. & Alvarez, P. (1995). Retrograde amnesia and memory consolidation: A neurobiological perspective. Current Opinion in Neurobiology, 5, 169–177.CrossRefGoogle ScholarPubMed
Thompson, S., Graham, K., Patterson, K., Sahakian, B., & Hodges, J. (2002). Is knowledge of famous people disproportionately impaired in patients with early and questionable Alzheimer’s disease? Neuropsychology, 16, 344–358.CrossRefGoogle ScholarPubMed
Twamley, E., Ropacki, S., & Bondi, M. (2006). Neuropsychological and neuroimaging changes in preclinical Alzheimer’s disease. Journal of the International Neuropsychological Society; JINS, 12, 707–735.CrossRefGoogle ScholarPubMed
Viskontas, I., McAndrews, M., & Moscovitch, M. (2002). Memory for famous people in patients with unilateral temporal lobe epilepsy and excisions. Neuropsychology, 16, 472–480.CrossRefGoogle ScholarPubMed
Vogel, A., Gade, A., Stokholm, J., & Waldemar, G. (2005). Semantic memory impairment in the earliest phase of Alzheimer’s disease. Dementia and Geriatric Cognitive Disorders, 19, 75–81.CrossRefGoogle ScholarPubMed
Wahlin, A., Backman, L., Mantyla, T., Herlitz, A., Viitanen, M., & Winblad, B. (1993). Prior knowledge and face recognition in a community-based sample of healthy, very old adults. Journal of Gerontology, 48, 54–61.CrossRefGoogle Scholar
Westmacott, R., Black, S., Freedman, M., & Moscovitch, M. (2004). The contribution of autobiographical significance to semantic memory: Evidence from Alzheimer’s disease, semantic disease, and amnesia. Neuropsychologia, 42, 25–48.CrossRefGoogle ScholarPubMed
Westmacott, R. & Moscovitch, M. (2003). The contribution of autobiographical significance to semantic memory. Memory & Cognition, 31, 761–774.CrossRefGoogle ScholarPubMed
Woodard, J., Seidenberg, M., Nielson, K., Miller, S., Franczak, M., Antuono, P., Douville, K., & Rao, S. (2007). Temporally graded activation of neocortical regions in response to memories of different ages. Journal of Cognitive Neuroscience, 19, 1113–1124.CrossRefGoogle ScholarPubMed