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Intensity-dependent facial emotion recognition and cognitive functions in Parkinson’s disease

Published online by Cambridge University Press:  27 July 2010

FRANCESCA ASSOGNA ,
FRANCESCO E. PONTIERI ,
LUCA CRAVELLO ,
ANTONELLA PEPPE ,
MARIANGELA PIERANTOZZI ,
ALESSANDRO STEFANI ,
PAOLO STANZIONE ,
CLELIA PELLICANO ,
CARLO CALTAGIRONE  and
GIANFRANCO SPALLETTA
FRANCESCA ASSOGNA
Affiliation:
I.R.C.C.S. Santa Lucia Foundation, Rome, Italy
FRANCESCO E. PONTIERI
Affiliation:
Department of Neurological Sciences, University “Sapienza”, Rome, Italy Movement Disorder Unit, Sant’Andrea Hospital, Rome, Italy
LUCA CRAVELLO
Affiliation:
I.R.C.C.S. Santa Lucia Foundation, Rome, Italy
ANTONELLA PEPPE
Affiliation:
I.R.C.C.S. Santa Lucia Foundation, Rome, Italy
MARIANGELA PIERANTOZZI
Affiliation:
Department of Neuroscience, University “Tor Vergata”, Rome, Italy
ALESSANDRO STEFANI
Affiliation:
Department of Neuroscience, University “Tor Vergata”, Rome, Italy
PAOLO STANZIONE
Affiliation:
Department of Neuroscience, University “Tor Vergata”, Rome, Italy
CLELIA PELLICANO
Affiliation:
Department of Neurological Sciences, University “Sapienza”, Rome, Italy Movement Disorder Unit, Sant’Andrea Hospital, Rome, Italy
CARLO CALTAGIRONE
Affiliation:
I.R.C.C.S. Santa Lucia Foundation, Rome, Italy Department of Neuroscience, University “Tor Vergata”, Rome, Italy
GIANFRANCO SPALLETTA*
Affiliation:
I.R.C.C.S. Santa Lucia Foundation, Rome, Italy
*
*Correspondence and reprint requests to: Gianfranco Spalletta, M.D., Ph.D., Laboratory of Clinical and Behavioral Neurology, I.R.C.C.S. Santa Lucia Foundation, Via Ardeatina, 306 – 00179 Rome, Italy. E-mail [email protected]
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Abstract

Patients with Parkinson’s disease (PD) frequently display non-motor symptoms. In this study, we investigated intensity-dependent facial emotion recognition in patients with PD and healthy controls (HC), matched for age, gender, and education, and its relationship to individual cognitive domains. Seventy patients with PD and 70 HC were submitted to a clinical, neuropsychological, and psychopathological evaluation. Facial emotion recognition performance was assessed using the Penn Emotion Recognition Test (PERT). The patients with PD recognized fewer low- and high-intensity facial expressions of disgust than HC. This effect was selective, because their global ability to recognize emotions was intact. Both patients with PD and HC recognized high-intensity better than low-intensity emotions, except for disgust, which was recognized better at low intensity. In the patients with PD, overall facial emotion recognition and selective disgust recognition performances were related to deficits in many neuropsychological domains (verbal and visuo-spatial memory, attention, praxis, and verbal fluency). The ability to recognize emotions is a complex cognitive process requiring the integrity of several functions. Therefore, it is likely that structural or functional derangement of the discrete neural pathways involved in these cognitive functions in patients with PD makes it difficult for them to recognize emotions expressed by others. (JINS, 2010, 16, 867–876.)

Keywords

Parkinson’s diseaseFacial expressionEmotion recognitionNon-motor symptomsCognitionNon-verbal communication
Type
Research Articles
Information
Journal of the International Neuropsychological Society , Volume 16 , Issue 5 , September 2010 , pp. 867 - 876
Copyright
Copyright © The International Neuropsychological Society 2010

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