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Impaired production priming and intact identification priming in Alzheimer's disease

Published online by Cambridge University Press:  11 January 2002

DEBRA A. FLEISCHMAN
Affiliation:
Rush-Presbyterian-St. Luke's Medical Center, Department of Neurological Sciences, Chicago, Illinois Rush Alzheimer's Disease Center, Chicago, Illinois
LAURA A. MONTI
Affiliation:
Rush-Presbyterian-St. Luke's Medical Center, Department of Neurological Sciences, Chicago, Illinois
LISA M. DWORNIK
Affiliation:
Rush-Presbyterian-St. Luke's Medical Center, Department of Neurological Sciences, Chicago, Illinois
TERESA T. MORO
Affiliation:
Rush-Presbyterian-St. Luke's Medical Center, Department of Neurological Sciences, Chicago, Illinois
DAVID A. BENNETT
Affiliation:
Rush-Presbyterian-St. Luke's Medical Center, Department of Neurological Sciences, Chicago, Illinois Rush Alzheimer's Disease Center, Chicago, Illinois
JOHN D.E. GABRIELI
Affiliation:
Rush-Presbyterian-St. Luke's Medical Center, Department of Neurological Sciences, Chicago, Illinois Stanford University, Department of Psychology, Palo Alto, California

Abstract

This study examined the distinction between identification and production processes in repetition priming for 16 patients with Alzheimer's disease (AD) and 16 healthy old control participants (NC). Words were read in three study phases. In three test phases, participants (1) reread studied words, along with unstudied words, in a word-naming task (identification priming); (2) completed 3-letter stems of studied and unstudied words into words in a word-stem completion task (production priming); and (3) answered yes or no to having read studied and unstudied words in a recognition task (explicit memory). Explicit memory and word-stem completion priming were impaired in the AD group compared to the NC group. After correcting for baseline slowing, word-naming priming magnitude did not differ between the groups. The results suggest that the distinction between production and identification processes has promise for explaining the pattern of preservation and failure of repetition priming in AD. (JINS, 2001, 7, 785–794.)

Type
Research Article
Copyright
© 2001 The International Neuropsychological Society

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