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Strongyloides stercoralis

Published online by Cambridge University Press:  21 June 2016

Deborah J. Zygmunt  and
Charles W. Stratton
Deborah J. Zygmunt*
Affiliation:
Division of Infectious Diseases, Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee
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Extract

Strongyloides stercoralis is a common nematode causing helminthic infections in humans. Strongyloidiasis is principally distributed in the tropics and subtropics. In the United States, a prevalence of 0.4% to 4% has been estimated in southeastern states. Like many other parasitic infections, strongyloidiasis most often is asymptomatic unless the patient becomes immunosuppressed. Immunosuppression can lead to an overwhelming autoinfection, which is highly fatal. This hyperinfection often occurs in hospitalized patients and may be confused with other nosocomial infections. This report will review the salient aspects of strongyloidiasis.

Type
Special Section
Information
Infection Control & Hospital Epidemiology , Volume 11 , Issue 9 , September 1990 , pp. 495 - 497
Copyright
Copyright © The Society for Healthcare Epidemiology of America 1990

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References

1. Milder, JE, Walzer, PD, Kilgore, G, Rutherford, I, Klein, M. Clinical features of Strongyloides stercomlis infection in an endemic area of the United States. Gastroenterology. 1981;80:1481–1488.10.1016/0016-5085(81)90261-4Google Scholar
2. Berk, SL, Verghese, A, Alvarez, S, Hall, K, Smith, B. Clinical and epidemiologic features of strongyloidiasis: a prospective study in rural Tennessee. Arch Intern Med. 1987;147:1257–1261.10.1001/archinte.1987.00370070071011CrossRefGoogle ScholarPubMed
3. Warren, KS. Helminthic diseases endemic in the United States. Am J Trop Med Hyg. 1974;23:723–730.Google Scholar
4. Igra-Siegman, Y, Kapila, R, Sen, P, Kaminski, ZC, Louria, DB. Syndrome of hyperinfection with Strongyloides stercoralis. Rev Infect Dis. 1981;3:397–407.10.1093/clinids/3.3.397Google Scholar
5. Rojas, RAM. Pathology of Protozoal and Helminthic Diseases. Baltimore, MD: Williams and Wilkins; 1971:713.Google Scholar
6. Brown, HW, Perna, VP. An overwhelming strongyloides infection. JAMA. 1958;168:1648–1651.10.1001/jama.1958.63000120004009bGoogle Scholar
7. Kyle, L, McKay, D. Strongyloidiasis. Ann Intern Med. 1948;29:1014–1042.Google Scholar
8. Yoeli, M, Most, H, Berman, HH, Tesse, B. The problem of strongyloidiasis among the mentally retarded in institutions. Trans R Soc Trop Med Hyg. 1963;57:336–345.10.1016/0035-9203(63)90096-8Google Scholar
9. Walzer, PD, Milder, JE, Banwell, JG, Kilgore, G, Klein, M, Parker, R. Epidemiologic features of Strongyloides stercoralis infection in an endemic area of the United States. Am J Trop Med Hyg. 1982;31:313–319.10.4269/ajtmh.1982.31.313Google Scholar
10. Pelletier, LL Jr. Chronic strongyloidiasis in World War II far east ex-prisoners of war. Am J Trop Med Hyg. 1984;33:55–61.10.4269/ajtmh.1984.33.55CrossRefGoogle Scholar
11. Purtilo, DT, Meyers, WM, Connor, DH. Fatal strongyloidiasis in immunosuppressedpatients. Am J Med. 1974;56:488–493.10.1016/0002-9343(74)90481-1Google Scholar
12. Boram, LH, Keller, KF, Justus, DE, Collins, JP. Strongyloidiasis in immunosuppressedpatients. Am J Clin Pathol. 1981;76:778–781.10.1093/ajcp/76.6.778CrossRefGoogle Scholar
13. Hinman, EH. A study of eighty-five cases of Strongyloides stercoralis infection, with special reference to abdominal pain. Trans R Soc Trop Med Hyg. 1937;30:531–538.10.1016/S0035-9203(37)90007-5CrossRefGoogle Scholar
14. Milner, PF, Irvine, RA, Barton, CJ, Bras, G, Richards, R. Intestinal malabsorption in Strongyloides stercoralis infestation. Gut. 1965;6:574–581.10.1136/gut.6.6.574Google Scholar
15. Jones, EV, Ogilvie, BM. Protective immunity to Nippostrongylus brasiliensis in the rat. Immunology. 1971;20:549–561.Google Scholar
16. Smith, JD, Goette, DK, Odom, RB. Larva currens: cutaneous strongyloidiasis. Arch Dermatol. 1976;112:1161–1163.10.1001/archderm.1976.01630320067021Google Scholar
17. Scowden, EB, Schaffner, W, Stone, WJ. Overwhelming strongyloidiasis; an unappreciated opportunistic infection. Medicine. 1978;57:527–544.10.1097/00005792-197811000-00004CrossRefGoogle ScholarPubMed
18. Cook, GC. Strongyloides stercoralis hyperinfection: how often is it missed. Q J Med. 1987;64:625–629.Google Scholar
19. Yee, A, Boylen, CT, Noguchi, T, Klatt, EC, Sharma, OP. Fatal Strongyloides stercoralis in a patient receiving corticosteroids. West J Med. 1987;146:363–364.Google Scholar
20. Morgan, JS, Schaffner, W, Stone, WJ. Opportunistic strongyloidiasis in renal transplant recipients. Transplantation. 1986;42:518–524.10.1097/00007890-198611000-00016Google Scholar
21. Maayan, S, Wormser, GP, Widerhorn, J, Sye, R, Kim, YH, Ernst, JA. Strongyloides stercoralis hyperinfection in a patient with the acquired immune deficiency syndrome. Am J Med. 1987;83:945–948.10.1016/0002-9343(87)90656-5Google Scholar
22. Jones, CA, Abadie, SH. Studies in human strongyloidiasis. II. A comparison of the efficency of diagnosis by examination of feces and duodenal fluid. Am J Clin Pathol. 1954;24:1154–1158.10.1093/ajcp/24.10.1154CrossRefGoogle Scholar
23. Beal, CB, Viens, P, Grant, RGL, Hughes, JM. A new technique for sampling duodenal contents: demonstration of upper small bowel pathogens. Am J Trop Med Hyg. 1970;19:349–352.10.4269/ajtmh.1970.19.349Google Scholar
24. Smith, B, Verghese, A, Guiterrez, C, Dralle, W, Berk, SL. Pulmonary strongyloidiasis: diagnosis by sputum gram stain. Am J Med. 1985;79:663–666.10.1016/0002-9343(85)90068-3Google Scholar
25. Genta, RM, Douce, R, Huitger, T. Immunodiagnosis of strongyloidiasis by ELISA. VA Pract. 1985;2:42–47.Google Scholar
26. Keystone, JS, Murdock, JK. Mebendazole. Ann Intern Med. 1979;91:582–586.10.7326/0003-4819-91-4-582CrossRefGoogle ScholarPubMed
27. Franz, KH. Clinical trials with thiabendazole against human strongyloidiasis. Am J Trop Med. 1963;12:211–214.10.4269/ajtmh.1963.12.211Google Scholar
28. Grove, DI. Treatment of strongyloidiasis with thiabendazole: an analysis of toxicity and effectiveness. Trans R Soc Trop Med Hyg. 1982;76:114–118.10.1016/0035-9203(82)90034-7Google Scholar
29. Seabury, JH, Abadie, S, Savoy, F Jr. Pulmonary strongyloidiasis with lung abscess: ineffectiveness of thiabendazole therapy. Am J Trop Med Hyg. 1971;20:209–211.10.4269/ajtmh.1971.20.209Google Scholar
30. Shelhamer, JH, Neva, FA, Finn, DR. Persistent strongyloidiasis in an immunodeficient patient. Am J Trop Med Hyg. 1982;31:746–751.10.4269/ajtmh.1982.31.746Google Scholar