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Efficacy of a Novel Light-Activated Antimicrobial Coating for Disinfecting Hospital Surfaces

Published online by Cambridge University Press:  02 January 2015

Salim Ismail ,
Stefano Perni ,
Jonathan Pratten ,
Ivan Parkin  and
Michael Wilson
Salim Ismail
Affiliation:
Division of Microbial Diseases, UCL Eastman Dental Institute, University College London, London, United Kingdom
Stefano Perni
Affiliation:
Division of Microbial Diseases, UCL Eastman Dental Institute, University College London, London, United Kingdom
Jonathan Pratten
Affiliation:
Division of Microbial Diseases, UCL Eastman Dental Institute, University College London, London, United Kingdom
Ivan Parkin
Affiliation:
Department of Chemistry, University College London, London, United Kingdom
Michael Wilson*
Affiliation:
Division of Microbial Diseases, UCL Eastman Dental Institute, University College London, London, United Kingdom
*
Division of Microbial Diseases, UCL Eastman Dental Institute, University College London, 256 Gray's Inn Road, London WCIX 8LD, United Kingdom ([email protected])
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Abstract

Silicone polymers containing the light-activated antimicrobial agent methylene blue with or without gold nanoparticles were evaluated for their ability to reduce the microbial load on surfaces in a clinical environment. When irradiated with white light, polymers containing nanogold were more effective in this respect than those containing only methylene blue.

Type
Concise Communications
Information
Infection Control & Hospital Epidemiology , Volume 32 , Issue 11 , November 2011 , pp. 1130 - 1132
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2011

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References

1.Decraene, V, Pratten, J, Wilson, M. Cellulose acetate containing toluidine blue and rose bengal is an effective antimicrobial coating when exposed to white light. Appl Environ Microbiol 2006;72:4436–4439.Google Scholar
2.Perni, S, Piccirillo, C, Pratten, J, et al. The antimicrobial properties of light-activated polymers containing methylene blue and gold nanoparticles. Biomaterials 2009;30:89–93.CrossRefGoogle ScholarPubMed
3.Decraene, V, Pratten, J, Wilson, M. An assessment of the activity of a novel light-activated antimicrobial coating in a clinical environment. Infect Control Hosp Epidemiol 2008;29:1181–1184.CrossRefGoogle Scholar
4.Murchan, S, Aucken, H, O'Neill, GL, et al. Emergence, spread, and characterization of phage variants of epidemic methicillin-resistant Staphylococcus aureus 16 in England and Wales. J Clin Microbiol 2004;42:5154–5160.Google Scholar
5. Chartered Institute of Building Service Engineers. CIBSE Lighting Guide LG2: Hospitals and Healthcare Buildings. 1989.Google Scholar
6.Usacheva, MN, Teichert, MC, Biel, MA. Comparison of the methylene blue and toluidine blue photobactericidal efficacy against gram-positive and gram-negative microorganisms. Lasers Surg Med 2001;29:165–173.Google Scholar
7.Decraene, V, Pratten, J, Wilson, M. Novel light-activated antimicrobial coatings are effective against surface-deposited Staphylococcus aureus. Curr Microbiol 2008;57:269–273.CrossRefGoogle ScholarPubMed