Hostname: page-component-cd9895bd7-7cvxr Total loading time: 0 Render date: 2025-01-01T00:18:42.367Z Has data issue: false hasContentIssue false
  • English
  • Français

Comparison of the Activities and Stabilities of Alkaline Glutaraldehyde Sterilizing Solutions

Published online by Cambridge University Press:  31 March 2016

Rollin E. Pepper
Rollin E. Pepper*
Affiliation:
Department of Biology, Elizabethtown College, Elizabeth-town, Pennsylvania
*
Department of Biology, Elizabethtown College, Elizabethtown, PA 17022
Get access Rights & Permissions [Opens in a new window]

Abstract

The sporicidal activities and shelf life stabilities of three alkaline glutaraldehyde-containing sterilizing solutions were evaluated. The time required to reduce a population of spores by one log is the D-value. The test methods employed were the D-value and survival rates. Sporicidin, a new preparation containing a phenolic buffer, was both more stable and more active against test spores than two other test agents, Cidex and Cidex-7.

Type
Research Article
Information
Infection Control & Hospital Epidemiology , Volume 1 , Issue 2 , April 1980 , pp. 90 - 92
Copyright
Copyright © The Society for Healthcare Epidemiology of America 1980

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1.Boucher, RMG. Advances in sterilization techniques, state of the art and recent breakthroughs. Am J Hosp Pharm 29:661–672, 1972.Google ScholarPubMed
2.Pepper, RE, Lieberman, ER. Dialdehyde alcoholic sporicidal composition. U.S. Patent No. 3,016,328, 1962.Google Scholar
3.Pepper, RE, Chandler, VL. Sporicidal activity of alkaline alcoholic saturated dialdehyde solutions. Appi Microbiol 11:384–388, 1963.Google Scholar
4.Stonehill, AA, Krop, S, Borick, PM. Buffered glutaraldehyde, a new chemical sterilizing solution. Am J Hosp Pharm 20:458–465, 1963.Google Scholar
5.Lin, KS, Park, MK, Baker, HA. Disinfection of anesthesia and respiratory therapy equipment with acid glutaraldehyde solution. RC 24:321–327, 1979.Google Scholar
6.Boucher, RMG. Stability of glutaraldehyde disinfectants during storage and use in hospitals. RC 23:1063–1072, 1978.Google Scholar
7.Borick, PM. Chemical Sterilizers (chemosterilizers). In: Advances in Applied Microbiology 10:302, 1968.Google Scholar
8.Thomas, S, Russell, AD. Temperature induced changes in the sporicidal activity and chemical properties of glutaraldehyde. Appi Microbiol 28:331–335, 1974.CrossRefGoogle ScholarPubMed
9.Miner, NA, McDowell, JW, Willcockson, GW, et al.Antimicrobial and other properties of a new stabilized alkaline glutaraldehyde disinfectant/sterilizer. Am J Hosp Pharm 34:376–382, 1977.Google Scholar
10.Boucher, RMG. Potentiated acid 1, 5 pentanedial solution, a new chemical sterilizing and disinfecting agent. Am J Hosp Pharm 31:546–557, 1974.Google Scholar
11.Schattner, RI. Buffered phenol-glutaraldehyde sterilizing composition. U.S. Patent No. 4,103, 001, 1978.Google Scholar
12.Russell, AD. Resistance of bacterial spores to heat, disinfectants, gases and radiation. Mfg Chem Aerosol News 36:38–45, 1965.Google Scholar
13.Horwitz, W. Official Methods of Analysis of the Association of Official Analytical Chemists, 12th ed. Washington, D.C., Association of Official Analytical Chemists, 1975.Google Scholar