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Pathogenesis of congenital cardiac malformations and mechanisms of cardiac remodelling

Published online by Cambridge University Press:  26 October 2005

Arnold C. G. Wenink  and
Adriana C. Gittenberger-de Groot
Arnold C. G. Wenink
Affiliation:
Department of Anatomy and Embryology, Leiden University Medical Center, Leiden, The Netherlands
Adriana C. Gittenberger-de Groot
Affiliation:
Department of Anatomy and Embryology, Leiden University Medical Center, Leiden, The Netherlands
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Extract

At first sight, the venous and arterial poles of the heart seem to belong to a single structure. This feature is demonstrated by the continuity seen in the fibrous skeleton between the leaflets of the aortic valve with those of both the mitral and tricuspid valves. Moreover, the orifice of the aortic valve is deeply wedged in between the fibrous annuluses supporting the two atrioventricular valves.

Keywords

Cardiac developmentdouble inlet left ventricleembryologyembryonic interventricular communication
Type
Second International Workshop
Information
Cardiology in the Young , Volume 15 , Supplement S3 , December 2005 , pp. 3 - 6
Copyright
© 2005 Cambridge University Press

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